PEMF Impacts Bone Healing at a Molecular, Cellular and Tissue Level
Spinal fusion is a standard of surgical care for many patients with lumbar or cervical disorders. While surgeons agree that the goal of spinal fusion is solid arthrodesis, this is difficult to achieve in patients at risk for non-union. Orthofix Spinal Fusion Stimulators generate a Pulsed Electromagnetic Field (PEMF) signal that stimulates bone cell growth at the molecular, cellular and tissue levels creating an environment more conducive to bone healing in patients at risk for a failed spinal fusion.
MOLECULAR
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Within 10 minutes of PEMF exposure, signaling pathways are activated.*Research on the molecular impact of PEMF demonstrates7-13:
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CELLULAR
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PEMF stimulates bone cells to proliferate, differentiate, and mineralize.*Research advances understanding of how PEMF facilitates bone growth at the cellular level9-13:
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TISSUE
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PEMF has been shown to improve the quality of bone tissue and enhance bone preservation.*Research documents PEMF’s significant effect on bone tissue.14-15:
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*PEMF has also been clinically proven to be a safe and effective noninvasive treatment to improve healing rates.16-17
Disclaimer: The results of pre-clinical studies may not be indicative of human clinical trials.
Statement of Indications
Spinal-Stim is a non-invasive electromagnetic bone growth stimulator indicated as an adjunct therapy to increase the probability of fusion success and as a non-operative treatment of salvage of failed spinal fusion, where a minimum of nine months has elapsed since the last surgery.
Cervical-Stim is a non-invasive, pulsed electromagnetic bone growth stimulator indicated as an adjunct therapy to cervical fusion surgery in patients at high-risk for non-union.