Top 3 Device Manufacturers in the U.S. Spine Market

In 2017, the total spine market in the United States (U.S.) was valued at over $7.7 billion USD. Of the many segments that make up this market, the minimally invasive spinal implants (MIS) segment is among the fastest-growing. It is interesting to note that the list of the top 3 competitors in the overall market coincides with that of the MIS market, albeit in different orders.

The top 3 competitors (by market share) in the U.S. spine market are Medtronic, DePuy Synthes and NuVasive. Technology concept. Human back, spine and gene chain.The top 3 competitors (by market share) in the U.S. spine market are Medtronic, DePuy Synthes and NuVasive. Photo Source:


Medtronic leads the U.S. spine market with nearly one-third of the total market share. The company consistently places within the top three competitors of the spinal implant market in which it actively competes. This includes the markets for cervical fixation, thoracolumbar fixation, interbody devices, motion preservation devices, vertebral compression fracture (VCF), surgery instrumentation, as well as MIS implants.

Medtronic gained the lead in both the VCF and motion preservation markets upon their acquisition of Kyphon in 2007. Medtronic’s strong position in the VCF market can be attributed to Kyphon’s former monopoly of the percutaneous vertebral augmentation market with their kyphoplasty product. However, Medtronic has lost significant shares in recent years to DePuy Synthes due to the success of their two artificial discs, which are now actually owned by Centinel Spine.

Medtronic’s leading position in the market will be continually challenged as new competitors in individual markets gradually erode the company’s share of the total market.

DePuy Synthes

DePuy Synthes closely competes with Medtronic as the second-leading competitor in the total spine market.

DePuy Synthes was founded in 1895 by a chemist and pharmaceutical salesman named Revra DePuy in Warsaw, Indiana. The company started as DePuy Manufacturing Company, a manufacturer of customized fiber splints. In 1998, Johnson & Johnson acquired DePuy and later, in 2012, Johnson & Johnson acquired Synthes, Inc., and combined those companies to create DePuy Synthes, one of the world’s largest orthopaedic and neurological businesses. The immensely successful merger allowed the organization to increase their market share in the spine industry, competing head-on with Medtronic for a market leading position.

DePuy Synthes is the market leader in the cervical fixation and interbody device markets. The company will remain a strong competitor in the spinal fusion market with its diverse line of traditional and MIS fusion devices. They were the only company with both a cervical artificial disc (CAD) and a lumbar artificial disc (LAD) on the U.S. market until DePuy Synthes sold their entire ProDisc artificial disc portfolio to Centinel Spine in late 2017.


NuVasive’s inclusion in this list can be attributed to its leading shares in the MIS market. The company’s shares in the MIS market are seven-times that of their shares in the traditional spine market.

While NuVasive continues to expand its presence in other areas of the spinal market, the XLIF® procedure (eXtreme Lateral Interbody Fusion) is one of the company’s best-known products. The XLIF procedure involves a lateral approach to the patient, rather than an anterior or posterior approach. When compared to traditional spine procedures that approach patients from the back or front and take many hours to complete, the XLIF procedure may be successfully completed in as little as one hour, reducing the length of time that the patient must be anesthetized.

The company has also expanded its fixation portfolio over a number of years to accommodate both open and minimally invasive approaches, as well as hybrid procedures. In addition, NuVasive produces several interbody devices for conventional spinal fusion. In 2017, the company announced expanded indications for its TLX™ Interbody System, used for conventional TLIF procedures (Transforaminal Lumbar Interbody Fusion). As NuVasive continues to grow its core business in the minimally invasive surgery market, it will further strengthen the company’s share in the interbody device market.

Other Notable Competitors

Other notable competitors in the U.S. spine market include Stryker, Zimmer Biomet, and Globus Medical. Stryker is the third-leading competitor in the traditional spine market, but has a much smaller presence in the MIS market therefore bringing its market share slightly below that of NuVasive. Evidently, the MIS segment has become an integral part of the total spine market and manufacturers who have capitalized on this trend early on are now reaping the benefits. It is expected that minimally invasive innovations will gradually cannibalize the traditional spine market.

For more on this spinal market research, the U.S. Market Report Suite for Spinal Implants and Vertebral Compression Fracture and U.S. Market Report Suite for Minimally Invasive Spinal Implants provide comprehensive reports on units sold, market values, average selling prices, procedure volumes, forecasts, as well as detailed competitive market shares and analysis of all major competitors.

iData’s global suite of reports on this subject cover the United States, Europe (15 countries), Asia-Pacific (Australia, China, Japan, South Korea, and Taiwan) and Latin America (Argentina, Brazil, and Mexico).

About iData Research
iData Research is an international consulting and market research firm, dedicated to providing the best in business intelligence for the medical device industry. Our research empowers our clients by providing them with the necessary tools to achieve their goals and do it right the first time.

Updated on: 09/03/19
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