Treatment Evaluation for Patients with Osteoporotic Vertebral Compression Fractures

Vertebroplasty at Levels Adjacent to Previous Fusions?

Percutaneous vertebroplasty (PV) is a safe and effective option for the treatment of osteoporotic vertebral compression fractures (OVCFs) that occur adjacent to circumferential fusion, according to the results of a new study. The study, “Clinical evaluation of percutaneous vertebroplasty for symptomatic adjacent vertebral compression fracture,” was conducted by researchers at E-Da Hospital/I-Shou University in Taiwan.
Doctors involved in research studyThe researchers set out to explore the efficacy of PV treatment in patients who were managing OVCFs following spinal fusion surgery for degenerative lumbar disease. The study was published online ahead of print in the Journal of Spinal Disorders and Techniques in October 2012.

Twenty-three patients were included in the retrospective study. All of the participants had undergone lumbar instrumented circumferential fusion, and they all suffered from adjacent OVCFs. The patients were treated at the researchers’ home institute using PV. Eighteen of the 23 patients were treated with 1 level PV; the remaining 5 patients were treated with 2-level PV.

To assess the patients’ conditions, the researchers relied on magnetic resonance imaging and radiography. Additionally, the Visual Analogue Scale (VAS) and modified Brodsky’s criteria were used prior to and after treatment. Patients were followed up with a minimum of 18 months following their surgery (maximum 45 months).

The study showed positive results for the use of PV to treat patients’ adjacent OVCFs. The patients’ VAS scores increased by an average of 54.3 points after their surgery. Twenty of the 23 patients found that they were able to engage in the normal daily activities they performed prior to their injury. In 4 patients, asymptomatic cement leakage occurred; however, no other post-surgical complications were found.

The researchers state that their study results indicate that percutaneous vertebroplasty is a minimally invasive, safe, and effective treatment option for people who have pain due to OVCFs adjacent to circumferential fusion.

Updated on: 05/30/17
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