Ibrahim Hussain, MD's portrait
Ibrahim Hussain, MD
Chief Resident Physician
Department of Neurosurgery
Weill Cornell Medical College/New York-Presbyterian Hospital
and Memorial Sloan Kettering Cancer Center
New York, NY

About Ibrahim Hussain, MD

Dr. Ibrahim Hussain is currently the Chief Resident Physician in the Department of Neurosurgery at Weill Cornell Medical College/New York-Presbyterian Hospital and Memorial Sloan Kettering Cancer Center. His areas of specialization include spine oncology, traumatic brain and spinal cord injuries, and minimally invasive and complex spinal deformity reconstruction.

Dr. Hussain received his Medical Degree from Rutgers-New Jersey Medical School in Newark with recognition by membership to the Alpha Omega Alpha Honor Society and a Doris Duke Research Fellowship focusing on neuro-oncology genomics at Washington University School of Medicine in St. Louis. During his residency, he has worked in the collaborative labs of Roger Härtl, MD, at Weill Cornell Medical College and Lawrence Bonassar, PhD, at Cornell University’s Meinig School of Biomedical Engineering in Ithaca, NY, where he is focusing on biological and stem-cell based innovations for disc regeneration and repair.

Furthermore, Dr. Hussain was the first resident in the history of the Department of Neurosurgery at Weill Cornell Medical College to be awarded the Charlie Kuntz Scholar Award in consecutive years and the Stewart Dunsker Award by the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS). These awards are presented in recognition of top research abstracts presented at their national conferences annually. He is an invited speaker and presents his research around the world.

Dr. Hussain has authored and co-authored more than 15 textbook chapters, including those in Neuroendoscopic Surgery, Surgery of the Thoracic Spine, Neurobiology of Disease, Complications in Neurosurgery, and the Surgical Atlas of Spinal Operations.



Peer-Reviewed Publications
1. Hussain I, Rapoport BI, Krause K, Kinney G, Hofstetter CP, Elowitz E. Transforaminal Endoscopic Lumbar Discectomy and Foraminotomy with Modified Radiofrequency Nerve Stimulator and Continuous Electromyography Under General Anesthesia: Technical Note. Submitted to World Neurosurgery, October 2019.

2. Hussain I, Winston G, Goldberg J, Curri C, Williams N, Chazen JL, Greenfield JP, Baaj AA. Impact of Imaging Modality, Age, and Gender on Craniocervical Junction Angles in Adults without Structural Pathology. Submitted to World Neurosurg, September 2019.

3. Hussain I, Cosar M, Kirnaz S, Schmidt F, Wipplinger C, Härtl R. Evolving 2D/3D Navigation, Robotics, and Augmented Reality in Minimally Invasive Spine Surgery. Submitted to Global Spine Journal, September 2019.

4. Kirnaz S, Hussain I, Baaj AA. Differential Rod Contouring with En Bloc Derotation Technique for Correction of Lenke 1A Adolescent Idiopathic Scoliosis. Submitted to Neurosurgical Focus, September 2019.

5. Hussain I, Kocharian G, Schwartz TS, Hoffman CE. Foundations of the Diagnosis and Treatment of Epilepsy. Submitted to World Neurosurg, November 2019.

6. Sadhwani S, Hussain I, Greenfield JP, Baaj AA. Achieving Neutral Physiologic Position During Occipitocervical Fusion: A Technical Note. Submitted to Oper Neurosurg (Hagerstown), September 2019.

7. Schmidt FA, Lekuya HM, Kirnaz S, Hernandez RN, Hussain I, Wipplinger C, Rawanduzy C, Härtl R. Novel MIS 3D NAV Single Step Pedicle Screw System (SSPSS): Workflow, Accuracy and Initial Clinical Experience. Submitted to Oper Neurosurg (Hagerstown), November 2019.

8. McCoy SP, Chidambaram MD, Hussain I, Askin G, Pannullo SP, Baaj AA. Early Outcomes and Complications in Intradural Spine Tumor Surgery: A Single-Surgeon Single-Institution Experience. Submitted to J Neurosurg Spine, August 2019.

9. Lener S, Wipplinger C, Hernandez RN, Hussain I, Kirnaz S, Navarro-Ramirez E, Schmidt FA, Kim E, Härtl R. Defining the MIS-TLIF: A Systematic Review of Techniques and Technologies Used by Surgeons Worldwide. Submitted to Global Spine Journal, July 2019.

10. Husain Q, Kim MH, Hussain I, Anand VK, Greenfield JP, Schwartz TH, Kacker A. Endoscopic Endonasal Approaches to the Craniovertebral Junction: The Otolaryngologist’s Perspective. Submitted to World Journal of Otorhinolaryngology-Head and Neck Surgery, June 2019.

11. Cheng L, Kirnaz S, Del Castillo-Calcaneo J, Hussain I, Härtl R. Fundamentals of Minimally Invasive Spine Surgery. Submitted to Indian Spine Journal, April 2019.

12. Kirnaz S, Wipplinger C, Schmidt FA, Hernandez RH, Hussain I, Härtl R. Laminotomy for Contralateral “Over the Top” Foraminal Decompression using 3D Total Navigation." Accepted, Oper Neurosurg (Hagerstown), February 2019.

13. Bustillo MA, Hussain I, Virk MS, Fu KM, Scharoun JH. Scoliosis Repair with One Ventricle: A Multispecialty Approach. Accepted to World Neurosurg, November 2019.

14. Kirnaz S, Navarro-Ramirez R, Gu J, Wipplinger C, Hussain I, Adjei J, Kim E, Schmidt FA, Hernandez RN, Härtl R. Indirect Decompression Failure after Lateral Lumbar Interbody Fusion: Reported Failures and Predictive Factors; Systematic Review. Accepted, Global Spine Journal, February 2019.

15. Hussain I, Nisson PL, Kim S, Baaj AA. Intradural Extramedullary Surgical Lysis of an Arachnoid Web of the Spine: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown), 2019.

16. Tundo F, Avila MJ, Willard L, Fanous S, Curri C, Hussain I, Baaj AA. Spinal Alignment, Surgery and Outcomes in Cervical Deformity: A Practical Guide to Aid the Spine Surgeon. Clin Neurol Neurosurg 185:105496, 2019.

17. Hussain I, Sloan SR, Wipplinger C, Navarro-Ramirez R, Zubkov M, Kim E, Kirnaz S, Bonassar LJ, Härtl R. Mesenchymal Stem Cell-Seeded High-Density Collagen Gel for Annular Repair: 6-Week Results From In Vivo Sheep Models. Neurosurgery 85:E350-E359, 2019.

18. Hussain I, Barzilai O, Reiner AS, McLaughlin L, DiStefano NM, Ogilvie S, Versteeg AL, Fisher CG, Bilsky MH, Laufer I. Spinal Instability Neoplastic Score Component Validation Using Patient-Reported Outcomes. J Neurosurg Spine:1-7, 2019.

19. Kirnaz S, Navarro-Ramirez R, Wipplinger C, Schmidt FA, Hussain I, Kim E, Härtl R. Minimally Invasive Transforaminal Lumbar Interbody Fusion Using 3-Dimensional Total Navigation: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown), 2019.

20. Nisson PL, Hussain I, Härtl R, Kim S, Baaj AA. Arachnoid Web of the Spine: A Systematic LIterature Review. J Neurosurg Spine:1-10, 2019.

21. Hussain I, Kirnaz S, Wibawa G, Wipplinger C, Härtl R. Minimally Invasive Approaches for Surgical Treatment of Lumbar Spondylolisthesis. Neurosurg Clin N Am 30:305-312, 2019.

22. Alalade AF, Ogando-Rivas E, Forbes J, Ottenhausen M, Uribe-Cardenas R, Hussain I, Nair P, Lehner K, Singh H, Kacker A, Anand VK, Härtl R, Baaj A, Schwartz TH, Greenfield JP. A Dual Approach for the Management of Complex Craniovertebral Junction Abnormalities: Endoscopic Endonasal Odontoidectomy and Posterior Decompression with Fusion. World Neurosurg X 2:100010, 2019.

23. Hussain I, Greenfield JP. Ultrasound-Guided Syringosubarachnoid Shunt Insertion for Cervicothoracic Syringomyelia. Clin Spine Surg, 2019.

24. Hernandez RN, Wipplinger C, Navarro-Ramirez R, Soriano-Solis S, Kirnaz S, Hussain I, Schmidt FA, Soriano-Sanchez JA, Härtl R. Ten-Step Minimally Invasive Cervical Decompression via Unilateral Tubular Laminotomy: Technical Note and Early Clinical Experience. Oper Neurosurg (Hagerstown), 2019.

25. Hussain I, Schmidt FA, Kirnaz S, Wipplinger C, Schwartz TH, Härtl R. MIS approaches in the Cervical Spine. J Spine Surg 5:S74-S83, 2019.

26. Mojica-Santiago JA, Lang GM, Navarro-Ramirez R, Hussain I, Härtl R, Bonassar LJ. Resorbable Plating System Stabilizes Tissue-Engineered Intervertebral Discs Implanted Ex Vivo in Canine Cervical Spines. JOR Spine 1:e1031, 2018.

27. Hussain I, Navarro-Ramirez R, Lang G, Härtl R. 3D Navigation-Guided Resection of Giant Ventral Cervical Intradural Schwannoma with 360-Degree Stabilization. Clin Spine Surg 31:E257-E265, 2018.

28. Hussain I, Baaj AA. Interbody Cage Versus Structural Allograft is Preferred for a 1-Level or 2-Level Anterior Cervical Discectomy and Fusion in a Nonsmoker. Clin Spine Surg, 2018.

29. Hussain I, Barzilai O, Reiner AS, DiStefano N, McLaughlin L, Ogilvie S, Bilsky M, Laufer I. Patient-Reported Outcomes After Surgical Stabilization of Spinal Tumors: Symptom-Based Validation of the Spinal Instability Neoplastic Score (SINS) and surgery. Spine J 18:261-267, 2018.

30. Pennicooke B, Hussain I, Berlin C, Sloan SR, Borde B, Moriguchi Y, Lang G, Navarro-Ramirez R, Cheetham J, Bonassar LJ, Härtl R. Annulus Fibrosus Repair Using High-Density Collagen Gel: An In Vivo Ovine Model. Spine (Phila Pa 1976) 43:E208-E215, 2018.

31. Navarro-Ramirez R, Berlin C, Lang G, Hussain I, Janssen I, Sloan S, Askin G, Avila MJ, Zubkov M, Härtl R. A New Volumetric Radiologic Method to Assess Indirect Decompression After Extreme Lateral Interbody Fusion Using High-Resolution Intraoperative Computed Tomography. World Neurosurg 109:59-67, 2018.

32. Sloan SR, Jr., Lintz M, Hussain I, Härtl R, Bonassar LJ. Biologic Annulus Fibrosus Repair: A Review of Preclinical In Vivo Investigations. Tissue Eng Part B Rev 24:179-190, 2018.

33. Hussain I, Virk MS, Link TW, Tsiouris AJ, Elowitz E. Posterior Lumbar Interbody Fusion with 3D-Navigation Guided Cortical Bone Trajectory Screws for L4/5 Degenerative Spondylolisthesis: 1-Year Clinical and Radiographic Outcomes. World Neurosurg 110:e504-e513, 2018.

34. Hussain I, Schwartz TH, Greenfield JP. Endoscopic Endonasal Approach to the Upper Cervical Spine for Decompression of the Cervicomedullary Junction Following Occipitocervical Fusion. Clin Spine Surg 31:285-292, 2018.

35. Lang G, Perrech M, Navarro-Ramirez R, Hussain I, Pennicooke B, Maryam F, Avila MJ, Härtl R. Potential and Limitations of Neural Decompression in Extreme Lateral Interbody Fusion-A Systematic Review. World Neurosurg 101:99-113, 2017.

36. Lang G, Navarro-Ramirez R, Gandevia L, Hussain I, Nakhla J, Zubkov M, Härtl R. Elimination of Subsidence with 26-mm-Wide Cages in Extreme Lateral Interbody Fusion. World Neurosurg 104:644-652, 2017.

37. Pennicooke B, Moriguchi Y, Hussain I, Bonssar L, Härtl R. Biological Treatment Approaches for Degenerative Disc Disease: A Review of Clinical Trials and Future Directions. Cureus 8:e892, 2016.

38. Hussain I, Husain Q, Baredes S, Eloy JA, Jyung RW, Liu JK. Molecular Genetics of Paragangliomas of the Skull Base and Head and Neck Region: Implications for Medical and Surgical Management. J Neurosurg 120:321-330, 2014.

39. Johnson KJ, Hussain I, Williams K, Santens R, Mueller NL, Gutmann DH. Development of an International Internet-Based Neurofibromatosis Type 1 Patient Registry. Contemp Clin Trials 34:305-311, 2013.

40. Gutmann DH, McLellan MD, Hussain I, Wallis JW, Fulton LL, Fulton RS, Magrini V, Demeter R, Wylie T, Kandoth C, Leonard JR, Guha A, Miller CA, Ding L, Mardis ER. Somatic Neurofibromatosis Type 1 (NF1) Inactivation Characterizes NF1-Associated Pilocytic Astrocytoma. Genome Res 23:431-439, 2013.

41. Hussain I, Eloy JA, Carmel PW, Liu JK. Molecular Oncogenesis of Craniopharyngioma: Current and Future Strategies for the Development of Targeted Therapies. J Neurosurg 119:106-112, 2013.

42. Hussain I, Duffis EJ, Gandhi CD, Prestigiacomo CJ. Genome-Wide Association Studies of Intracranial Aneurysms: An Update. Stroke 44:2670-2675, 2013.

43. Thaker NG, Turner JD, Cobb WS, Hussain I, Janjua N, He W, Gandhi CD, Prestigiacomo CJ. Computed Tomographic Angiography Versus Digital Subtraction Angiography for the Postoperative Detection of Residual Aneurysms: A Single-Institution Series and Meta-Analysis. J Neurointerv Surg 4:219-225, 2012.

44. Hussain I, Gutmann DH. Molecular Genetics of Optic Glioma – Lessons Learned from Neurofibromatosis-1 Genetically Engineered Mice. Expert Review of Ophthalmology 6:363-369, 2011.

Book Chapters
1. Härtl R, Del Castiollo- Calcáneo, Kirnaz S, Hussain I. Definition of MISS: The 6 T’s: Target / Technology / Technique / Teaching & Training/ Testing / Talent, in Härtl R, Navarro-Ramirez R (eds.) Ten Step Techniques for Minimally Invasive Spine Surgery. New York: Thieme Medical Publishers, Submitted, 2019.

2. Hussain I, Navarro-Ramirez R, Kirnaz S, Härtl R. Technique: 3 Surgical Principles of MIS: Contralateral Decompression, Minimize Instability, Indirect Decompression, in Härtl R, Navarro-Ramirez R (eds.) Ten Step Techniques for Minimally Invasive Spine Surgery. New York: Thieme Medical Publishers, Submitted, 2019.

3. Schwarz J, Boddu S, Hussain I, Santillan A, Patsalides A. 10 steps: Thoracic Vertebroplasty/Kyphoplasty, in Härtl R, Navarro-Ramirez R (eds.) Ten Step Techniques for Minimally Invasive Spine Surgery. New York: Thieme Medical Publishers, Submitted, 2019.

4. Hussain I, Pennicooke BH, Baaj AA. Introduction to Spinal Metastases – Foundations, in Ramakrishna R, Knisley J, Magge R, and Baaj AA (eds.) Central Nervous System Metastases: Diagnosis and Treatment. New York: Springer. In Press, 2019.

5. Pennicooke BH, Hussain I, Baaj AA. Spinal Metastases - Decision Making Algorithm for Surgical Treatment (Classifications schema, etc.), in Ramakrishna R, Knisley J, Magge R, and Baaj AA (eds.) Central Nervous System Metastases: Diagnosis and Treatment. New York: Springer. In Press, 2019.

6. Schwarz J, Hussain I, Santillan A, Kutler D, Knopman J. Paraganglioma Embolization, in Park MS, Kalani YS, and Stiefel MF (eds.) Neurointerventional Surgery: An Evidence Based Approach. New York: Springer Press. In Press 2019.

7. Hussain I, Härtl R, Baaj AA. Tubular Discectomy, in Eck JC and Vaccaro AR (eds.) Surgical Atlas of Spinal Operations, 2nd Edition. New Delhi: Jaypee Brothers Medical Publishers. In Press, 2019.

8. Singh H*, Hussain I*, Schwartz TH (*equal contributors). Endoscopic Assisted Supraorbital Key-hole Approach, in Castelnuovo P, Dallan I (eds.) Multiportal Endoscopic Approaches to the Skull Base. Amsterdam: Elsevier. In Press, 2019.

9. Goldberg J, Hussain I, Greenfield JP, Baaj AA. How to Revise a Failed Suboccipital Decompression for Chiari Malformation, in Vaccaro AR, Schroeder GD, Baaj AA (eds.) Revision Spine Surgery: Pearls and Pitfalls. Oxford: Taylor and Francis. 10:65-74, 2019.

10. Hussain I, Morgenstern PF, Baaj AA. Treatment of Ventral Thoracic Dural Defects, in Vaccaro AR, Schroeder GD, Baaj AA (eds.) Revision Spine Surgery: Pearls and Pitfalls. Oxford: Taylor and Francis. 34:243-247, 2019.

11. Hussain I, Baaj AA. Intradural Extramedullary Tumors, in Baaj AA, Kakala K, Kim HJ (eds.) Surgery of the Thoracic Spine. New York: Thieme Medical Publishers. 21:180-184, 2019.

12. Hussain I, Laufer I, Bilsky M. Complications of Surgery and Radiosurgery in Spinal Metastasis, in Nanda A (ed.) Complications in Neurosurgery, 1st Edition. New York: Elsevier. 60:356-361, 2018.

13. Lang G, Hussain I, Zubkov M, Moriguchi Y, Pennicooke B, Härtl R. Summary of Clinical Trials with Biological Treatment Approaches for Spinal Disease, in Härtl R and Bonassar LJ (eds.) Biological Approaches to Spinal Disc Repair and Regeneration for Clinicians. New York: Thieme Medical Publishers. 16:140-150, 2017.

14. Singh H, Essayed WI, Hussain I, Yang K, Anand VK, Schwartz TH. Endoscopic Transsphenoidal Pituitary Surgery: Results and Complications, in Laws ER, Cohen-Gadol AA, Schwartz TH, Sheehan JP (eds.) Transsphenoidal Surgery-Complication Avoidance and Management Techniques. New York: Springer Press. 15:245-249, 2017.

15. Hussain I, Gutmann DH. Familial CNS Tumor Syndromes: Neurofibromatosis Type 1, in Gilman S (ed.) Neurobiology of Disease, 2nd Edition. New York: Oxford University Press. 134: 970-977, 2016.

16. Cisse B, Hussain I, Greenfield JP, Long CS. Birth Trauma to the Scalp and Skull, in Greenfield JP & Long CS (eds.) Common Neurosurgical Conditions in the Pediatric Practice: Recognition and Management. New York: Springer Press. 3:27-33, 2016.

17. Kapoor R, Hussain I, Hoffman CE, Stieg PE. Basic Neurosurgical Procedures, in Britz GW (ed.) Comprehensive Guide for Patients and Families with Neurosurgical Conditions and Emergencies. New York: Springer Press. 7:59-73, 2015.

18. Hussain I, Abdel-Latif AM, Souweidane MM. Intraventricular and Paraventricular Tumors, in Torres-Corzo JG, Rangel-Castilla L, & Nakaji P (eds.) Neuroendoscopic Surgery. New York: Thieme Medical Publishers. 12:127-144, 2015.

19. Kaul A, Hussain I, Gutmann DH.  Using Genetically-Engineered Mouse Models to Understand Low-Grade Glioma Development and Growth in Children, in Martinez-Murillo R, Martinez A (eds.) Animal Models of Brain Tumors – Neuromethods Series.  New York: Springer Press. 77:203-215. 2012.

Case Studies Presented by Ibrahim Hussain, MD

Revision Surgery for Pseudarthrosis after Thoracolumbar Fracture Stabilization

Presented by: A. Baaj MD, I. Hussain MD
Adult male sustained L1 and L2 fractures during a helicopter crash. One year after treatment elsewhere, the patient presents with pseudarthrosis and debilitating back pain.

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