Amer Khalil, MD's portrait
Amer Khalil, MD
Director of Spine Surgery
Department of Neurological Surgery
University of California Irvine
Irvine, CA
Dr. Khalil is a member of the SpineUniverse Editorial Board.

About Amer Khalil, MD

Dr. Amer Khalil is Director of Spine Surgery, Department of Neurological Surgery at the University of California Irvine. Dr. Khalil is a board certified and fellowship-trained neurosurgeon in practice at DISC Sports & Spine located in Newport Beach, CA specializing in complex and minimally invasive spine surgery.

Dr. Khalil's clinical interests include cervical and lumbar spine surgery, complex deformity surgery and scoliosis, lateral access and minimally invasive surgical procedures, spine fractures, spinal cord injury, spinal tumors, spondylosis, and spondylolisthesis. Dr. Khalil has special interest in innovative therapies and technologies to improve the health of patients.

Dr. Khalil completed an internship in general surgery and residency in neurological surgery at the Cleveland Clinic Foundation in Cleveland, OH. Thereafter, Dr. Khalil underwent combined neurosurgery-orthopaedic spine surgery fellowship at New England Baptist Hospital in Boston, MA, and a research fellowship in Spinal Cord Injury at Massachusetts Institute of Technology in Boston conducting preclinical trials of neuroscaffolds implantation in injured spinal cord of rats that led to the first-in-human clinical trial.

Dr. Khalil also held fellowship positions in neurosurgery at Harvard affiliated hospitals, Boston Children's Hospital, Brigham and Women's Hospital, and Beth Israel Deaconess Hospital in Boston, MA. He earned his Doctor of Medicine degree at University of Jordan Medical School in Amman, Jordan.

Throughout his academic career, Dr. Khalil has received many honors, including the American Association of Neurological Surgeons Top Gun Award.

Dr. Khalil is an active member of the American Association of Neurological Surgeons (AANS), Congress of Neurological Surgeons (CNS), AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves, North American Spine Society (NASS), AO Spine foundation, Spinal Cord Injury Foundation, and several other societies.


Peer-Reviewed Publications
Khalil A, Spiotta AM, Barnett GH. Difficulties with the neurological assessment of humans following a chimpanzee attack. J Neurosurg. 2011 Jul;115(1):140-4.

Klimo P Jr., Khalil A, Slotkin JR, Smith ER, Scott RM, Goumnerova LC. Wound complications associated with the use of bovine serum albumin-glutaraldehyde surgical adhesive in pediatric patients. Neurosurgery. 2007 Apr;60(4 Suppl 2):305-9.

Manuscripts in Preparation
Reynolds FM, Woodard EJ, Slotkin JR, Dai H, Luque B, Ye J, Layer RT, Pritchard CD, Khalil A, Lawrence MS, O’Shea TM,Roy RR, Zhong H, Vollenweider I, Edgerton VR, Courtine G, Langer RS. Porous biodegradable polymeric scaffolds promote tissue remodeling and functional improvement in non-human primates with spinal cord injury.

Presentations and Posters
Kwon B, Khalil A. Accuracy of fluoroscopically-assisted percutaneous pedicle Screws placed in patients in the lateral decubitus position. SMISS Global Forum, 2015.

Dai H, Layer R, O’Shea T, Hou J, Khalil A, Podell P, Hess B, Aimetti A, Huang, G, Reynolds F. Effect of porous PLGA-PLL scaffolds on recovery following spinal contusion injury in rats. Neurotrauma Society, 2013.

Khalil A. Endoscopic lamina terminalis fenestration for treatment of obstructive hydrocephalus following failed ETV. AANS, 2010.

Khalil A, Deogaonkar M. Peripheral nerve/field stimulation for post-intervention trigeminal neuropathic pain. CNS, 2010.

Khalil A, Barnett G. Difficulties with the neurological assessment of humans after chimpanzee attack. CNS, 2009.

Khalil A, Tierney T, Smith E. Case Report: Double split cord malformation, a novel type of congenital split cord. AANS, 2007.

Kim A, Khalil A, Black P, Golby A. Simultaneous multiple craniotomies for multiple metastatic lesions. CNS, 2006.

Articles Written by Amer Khalil, MD

10 Tips to Make Your Spine Care Experience Safer

As you work with medical professionals, remember you are a consumer of health services—and you’re more in control than you may think.

Case Studies Presented by Amer Khalil, MD

Thoracic Exophytic Ependymoma With Severe Spinal Cord Compression

Presented by: A. Khalil MD
A 50-year-old female presented wheelchair bound with progressive lower extremity weakness and numbness. She has diffuse numbness in the lower abdomen and both legs, and bowel and bladder dysfunction.

Acute Traumatic Central Cord Syndrome

Presented by: B. Ball MD, C. Christie MD, J. Chen MD, A. Khalil MD
A 73-year-old male who was in a motor vehicle accident presented with diffuse weakness and numbness in both arms and legs; symptoms were worse in his hands.

Failure to Recognize Traumatic Cervical Spinal Instability, C7-T1 Traumatic Cervical Spine Deformity

Presented by: A. Khalil MD
An elderly male who suffered C7 and T1 fractures status post a motor vehicle accident, presented to our clinic 2 months after the initial injury with worsening neck deformity and new right hand weakness and numbness.

Traumatic Unilateral Cervical Spine Perched Facet

Presented by: B. Ball MD, S. Kaloostian MD, A. Khalil MD
A 22-year-old male was evaluated in the ED after a motor vehicle collision. He was found to have bilateral C6 comminuted lamina fractures extending to the right C6-C7 facets with grade 1 anterolisthesis of the C6 vertebral body, and perched right C6-C7 facet.

Chronic Type II Odontoid Fracture With C1-C2 Instability and Severe Spinal Cord Compression

Presented by: A. Khalil MD
Case report of an adult female with history of an old type II odontoid fracture presented with severe mechanical neck pain, progressive upper and lower extremity symptoms, and gait difficulties.

Central Cord Syndrome With Type II Odontoid Fracture

Presented by: A. Khalil MD
Central cord syndrome, severe spinal canal stenosis and type II odontoid fracture in an older male adult is featured in this case report.

Cervical Spine Multiple Myeloma With Kyphotic Deformity and Cervical Myelopathy

Presented by: A. Khalil MD
The patient is a 60-year-old female with a history of multiple myeloma and worsening mechanical neck pain. Associated symptoms include increased arm and leg weakness with numbness and gait difficulties.

Articles Reviewed by Amer Khalil, MD

Arachnoid Web of the Spine: Optimal Detection and Management

Systematic review of surgically treated patients with arachnoid web of the spine provides a comprehensive review of the published literature on AWS to help physicians who see these patients.

Financial Disclosures

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Author's Statement

I, the undersigned, declare that neither I nor members of my immediate family have a financial interests or affiliation with commercial companies whose products and / or services may be mentioned in the materials I have authored, edited or reviewed for presentation on Remedy Health Media, LLC’s websites.