Thomas A Kosztowski, MD's portrait
Thomas A Kosztowski, MD
Neurosurgeon
Johns Hopkins Hospital
Baltimore, MD

About Thomas A Kosztowski, MD

Dr. Thomas Kosztowski is a fellowship trained neurosurgical resident at Johns Hopkins Hospital in Baltimore, MD.

Dr. Kosztowski received his medical degree at Johns Hopkins School of Medicine and completed his internship in general surgery and neurosurgery at Johns Hopkins Hospital. During his residency, he completed the prestigious Johns Hopkins Spine Center's Enfolded Complex Spine Fellowship program under the tutelage of Ziya Gokaslan, MD, FACS. Throughout his academic career, he has received many honors and awards.

Dr. Kosztowski has published nearly 30 papers in peer reviewed journals and has co-authored 15 chapters in spine textbooks. Furthermore, his research has been featured in abstracts and posters, and the subject of his many presentations. Since 2013, he has conducted research at Johns Hopkins' Spinal Outcomes and Biomechanics Laboratory.

Publications

Peer Reviewed Publications
Goodwin CR, Sankey EW, Liu A, Elder BD, Kosztowski T, Lo SL, Fisher CG, Clarke MJ, Gokaslan ZL, Sciubba DM. A systematic review of clinical outcomes for patients diagnosed with skin cancer spinal metastases. J Neurosurg Spine. 2015 Nov 6:1-13.

Kosztowski T, Goodwin CR, Gokaslan ZL. Perspective on Ionizing Radiation Exposure to Neurosurgery Residents in the Modern Era. World Neurosurg. 2015 Oct 31. pii: S1878-8750(15)01392-3. doi: 10.1016/j.wneu.2015.10.048.

Elder BD, Sankey EW, Theodros D, Bydon M, Rory Goodwin C, Lo SF, Kosztowski TA, Belzberg AJ, Wolinsky JP, Sciubba DM, Gokaslan ZL, Bydon A, Witham TF. Successful anterior fusion following posterior cervical fusion for revision of anterior cervical discectomy and fusion pseudarthrosis. J Clin Neurosci. 2015 Oct 16. pii: S0967-5868(15)00450-6. doi: 10.1016/j.jocn.2015.07.019.

Goodwin CR, Khattab MH, Sankey EW, Elder BD, Kosztowski TA, Sarabia-Estrada R, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Factors Associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung. Global Spine J. 2015 Oct;5(5):417-24. doi: 10.1055/s-0035-1554778. Epub 2015 Jun 5.

Liu A, Sankey EW, Godwin CR, Kosztowski TA, Elder BD, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Postoperative survival and functional outcomes for patients with metastatic gynecological cancer to the spine: case series and review of the literature. J Neurosurg Spine. 2015 Sep 11:1-14. 

Goodwin CR, Sankey EW, Jusué-Torres I, Elder BD, Kosztowski TA, Liu A, Hoffberger J, Lu J, Blitz AM, Rigamonti D.  The Use of an Aspirating/Resecting Device to Reduce Stoma Closure Following Endoscopic Third Ventriculostomy for Aqueductal Stenosis. Neurosurgery. 2015 Jul 29.

Goodwin CR, Abu-Bonsrah N, Kosztowski T, Bydon A, Sciubba DM. Thoracic pneumorachis. Spine J. 2015 Jul 26. pii: S1529-9430(15)01153-5. doi: 10.1016/j.spinee.2015.07.445.

Elder BD, Lo SF, Kosztowski TA, Goodwin CR, Lina IA, Locke JE, Witham TF.

A systematic review of the use of expandable cages in the cervical spine. Neurosurg Rev. 2015 Jul 28.

Bydon M, Macki M, Qadi M, De la Garza-Ramos R, Kosztowski TA, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A. Regression of an atlantoaxial rheumatoid pannus following posterior instrumented fusion. Clin Neurol Neurosurg. 2015 Oct;137:28-33. doi: 10.1016/j.clineuro.2015.06.010. Epub 2015 Jun 18.

Elder BD, Lo SF, Holmes C, Goodwin CR, Kosztowski TA, Lina IA, Locke J, Witham TF. The Biomechanics of Pedicle Screw Augmentation with Cement. Spine J. 2015 Mar 19. pii: S1529-9430.

Elder BD, Holmes C, Goodwin CR, Lo SF, Puvanesarajah V, Kosztowski TA, Locke JE, Witham TF. A Systematic Assessment of the Use of Platelet-Rich Plasma in Spinal Fusion. Ann Biomed Eng. 2015 Mar 21

Moran D, Kosztowski TA, Jusué-Torres I, Orkoulas-Razis D, Ward A, Carson K, Hoffberger J, Elder BD, Goodwin CR, Rigamonti D.  Does CT wand guidance improve shunt placement in patients with hydrocephalus? Clin Neurol Neurosurg. 2015 May;132:26-30.

Lo SF, Otake Y, Puvanesarajah V, Wang AS, Uneri A, De Silva T, Vogt S, Kleinszig G, Elder BD, Goodwin CR, Kosztowski TA, Liauw JA, Groves M, Bydon A, Sciubba DM, Witham TF, Wolinsky JP, Aygun N, Gokaslan ZL, Siewerdsen JH.  Automatic Localization of Target Vertebrae in Spine Surgery: Clinical Evaluation of the LevelCheck Registration Algorithm. Spine (Phila Pa 1976). 2015 Apr 15;40(8):E476-83. 

Elder BD, Rory Goodwin C, Kosztowski TA, Radvany MG, Gailloud P, Moghekar A, Subramanian PS, Miller NR, Rigamonti D.  Venous sinus stenting is a valuable treatment for fulminant idiopathic intracranial hypertension. J Clin Neurosci. 2015 Apr;22(4):685-9

Goodwin CR, Elder BD, Ward A, Orkoulas-Razis D, Kosztowski TA, Hoffberger J, Moghekar A, Radvany M, Rigamonti D. Risk factors for failed transverse sinus stenting in pseudotumor cerebri patients.Clin Neurol Neurosurg. 2014 Dec;127:75-8

Brastianos PK, Brastianos HC, Hsu W, Sciubba DM, Kosztowski T, Tyler BM, Recinos VR, Burger P, Grossman SA. The toxicity of intrathecal bevacizumab in a rabbit model of leptomeningeal carcinomatosis. Journal of Neurooncology. 2012 Jan;106(1):81-8.

Hsu W, Mohyeldin A, Shah SR, ap Rhys CM, Johnson LF, Sedora-Roman NI, Kosztowski TA, Awad OA, McCarthy EF, Loeb DM, Wolinsky JP, Gokaslan ZL, Quiñones-Hinojosa A. Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target. Journal of Neurosurgery. 2011 Oct;115(4):760-9. 

Hsu W, Kosztowski TA, Zaidi HA, Gokaslan ZL, Wolinsky JP. Image-Guided, Endoscopic Transcervical Resection of Cervical Chordoma.  Journal of Neurosurgery-Spine.   2010 Apr;12(4):431-5. 

Chaichana KL, Kosztowski T, Niranjan A, Olivi A, Weingart JD, Laterra J, Brem H, Quiñones-Hinojosa A. Prognostic significance of contrast-enhancing anaplastic astrocytomas in adults. Journal of Neurosurgery. 2010 Aug;113(2):286-92.

Mukherjee D,  Zaidi HA,  Kosztowski TA, Chaichana KL, Brem H, Chang DC, Quinones-Hinojosa A. “Disparities in access to neuro-oncological care in the United States.” Archives of Surgery Journal,  2010 Mar;145(3):247-53. 

Mukherjee D, Zaidi HA, Kosztowski TA, Halthore A, Jallo GI, Salvatori R, Chang DC, Quiñones-Hinojosa A. Variations in referral patterns for hypophysectomies among pediatric patients with sellar and parasellar tumors. Child’s Nervous System Journal. 2010 Mar;26(3):305-11.

Mukherjee D,  Kosztowski TA, Zaidi HA, Jallo GI, Carson B, Chang DC, Quinones-Hinojosa A. “Disparities in access to pediatric neurooncological care in the United States.” Pediatrics, 2009 Oct;124(4).

Recinos VR, Bekelis K, Ziegler SG, Vick D, Hertig S, Tyler BM, Li KW, Kosztowski T, Legnani FG, Brem H, Olivi A. Epirubicin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers. Journal of Neuro-Oncology  2010 Mar;97(1):1-10.

Hsu W, Kosztowski TA, Zaidi HA, Adams HA, Gokaslan ZL, Wolinsky JP. Multidisciplinary management of primary tumors of the vertebral column. Current Treatment Options in Oncology, 2009 Apr;10(1-2):107-25.

Zaidi HA, Kosztowski TA, Quinones-Hinojosa A. Mesenchymal Stem Cells—A single source for both spinal cord regeneration and tumor therapy. Journal of Spinal Research Foundation, 2009.

Mukherjee D,  Zaidi HA,  Kosztowski TA, Chaichana KL, Salvatori R, Chang DC, Quinones-Hinojosa A. Predictors of Access to Pituitary Tumor Resection in the United States, 1988-2005 European Journal of Endocrinology, 2009 Apr;10(1-2).

Kosztowski TA, Zaidi HA, Quinones-Hinojosa A. Applications of Neural and Mesenchymal Stem Cells in the Treatment of Gliomas. Expert Review in Anticancer Therapy Journal, 2009 May;9(5):597-612.

Zaidi HA, Kosztowski TA, Quinones-Hinojosa A. Origins and Clinical Implications of the Brain Tumor Stem Cell Hypothesis. Journal of Neuro-Oncology, 2009 May;93(1):49-60.

Sanders JM, Song Y, Chan JM, Zhang Y, Jennings S, Kosztowski T, Odeh S, Flessner R, Schwerdtfeger C, Kotsikorou E, Meints GA, Gomez AO, Gonzalez-Pacanowska D, Raker AM, Wang H, van Beek ER, Papapoulos SE, Morita CT, Oldfield E. 2005. Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. Journal of Medicinal Chemistry.  Apr 21 ;48(8):2957-63.

Hudock MP, Sanz-Rodriguez CE, Song Y, Chan JM, Zhang Y, Odeh S, Kosztowski T, Leon-Rossell A, Concepcion JL, Yardley V, Croft SL, Urbina JA, Oldfield E.  Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.  Journal of Medicinal Chemistry. 2006 Jan 12;49(1):215-23.

Book Chapters
Kosztowski TA, Rhee, J, Bydon M, Gokaslan Z. Craniocervical Reseconstruction After Chordoma Resection. Chordomas. Al Mefty O, Borba LAB  L, Pami NM (eds).  (In press)

Kosztowski TA, Bydon M, Goodwin RC, Gokaslan Z. Surgery for Spinal Chordomas. Chordomas. Al Mefty O, Borba LAB  L, Pami NM (eds). (In press)

Kosztowski TA, Bydon M, Wolinsky JP, Gokaslan Z. Primary and Metastatic Tumors of the Thoracic Spine: Total En Bloc Spondylectomy. Spine Surgery: A Neurosurgical Approach. Van de Kelf E (ed). (In press)

Goodwin CR, Kosztowski TA, Elder B, Sciubba DM. Lumbosacropelvic Fixation Techniques.  Spine Surgery: Techniques, Complication Avoidance, and Management.. 4th Edition. Benzel EC (ed). (In press)

Rhee J, Kosztowski, Bydon M, Gokaslan.  Sacral Tumor: Regional Challenge. Spine Surgery: Techniques, Complication Avoidance, and Management.. 4th Edition. Benzel EC (ed). (In press)

Wolinsky JP, Kosztowski, Bydon M, Gokaslan. Spondylectomy for Spinal Tumors. Spine Surgery: Techniques, Complication Avoidance, and Management.  4th Edition. Benzel EC (ed).  (In press)

Kosztowski TA, Bydon M, Gokaslan Z. Sacrectomy.  Handbook of Spine Surgery, 2nd Edition. Baaj A (ed) (In press)

Kosztowski TA, Bydon M, Goodwin RC, Gokaslan Z.   Cervucothoracic Tumor Resections and Reconstructions of the Cervicothoracic Junction.  Turkish Spine Society: Diagnosis and Treatment of Spine Tumor Spinal Oncology. Aydinli U, Kahraman S (ed). (In press)

Kosztowski TA, Bydon M, Gokaslan Z. Review of “Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial” by Patchell et al 2005 Lancet study.” CNS Essentials of Neurosurgery. Hoh, DJ,  Ghogawala, Z.(ed). (In press)

Olivi A, Kosztowski TA, Bydon M, Goodwin CR. “Brain Tumors During Pregnancy.” Youmans Neurological Surgery -7th Edition. Winn HR, Quinones-Hinojosa A (ed).

Quinones-Hinojosa A, Kosztowski TA, Brem H. “Malignant Gliomas: Anaplastic Astrocytoma, Glioblastoma Multiforme, Gliosarcoma.” Youmans Neurological Surgery -6th Edition. Winn HR (ed).

Kosztowski TA, Filippidis SA, Goodwin RC, Elder BD, Rigamonti D. “Anatomy and physiology of the cerebrospinal fluid system.”  Adult Hydrocephalus. 1st Edition. Cambridge Publishing.

Elder BD, Bankah P, Blitz AM, Goodwin RC, Kosztowski TA, Jusué-Torres I,  Rigamonti D. “Core imaging in adult hydrocephalus.” Adult Hydrocephalus. 1st Edition.  Cambridge Publishing. 

Elder BD, Goodwin RC, Kosztowski TA, Rigamonti D. “Hydrocephalus shunt procedures.”  Adult Hydrocephalus. 1st Edition.  Cambridge Publishing. 

Elder BD, Goodwin RC, Kosztowski TA, Rigamonti D. “Normal pressure hydrocephalus syndrome secondary to hemorrhage, infection and, malignancy.” Adult Hydrocephalus. 1st Edition.  Cambridge Publishing.

Posters and Abstracts
Goodwin CR, Khattab MH, Sankey EW, Elder BD, Kosztowski TA, Sarabia-Estrada R, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Factors associated with Life Expectancy in Patients with Metastatic Spine Disease from Adenocarcinoma of the Lung. Accepted to Congress of Neurological Surgeons 2015 Annual Meeting. New Orleans, LA. September 26-30, 2015.

Goodwin CR, Sankey EW, Liu A, Elder BD, Kosztowski TA, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Primary Lesion Location Influences Postoperative Survival in Patients with Metastatic Colorectal Spinal Lesions. Accepted to Congress of Neurological Surgeons 2015 Annual Meeting. New Orleans, LA. September 26-30, 2015.

Goodwin CR, Liu A, Sankey EW, Kosztowski TA, Elder BD, Sciubba DM. Postoperative survival and functional outcomes of Metastatic Gynecological Cancer to the Spine: Case Series and review of the literature. Accepted to Congress of Neurological Surgeons 2015 Annual Meeting. New Orleans, LA. September 26-30, 2015.

Goodwin CR, Sankey EW, Liu A, Elder BD, Kosztowski TA, Lo SL, Fisher C, Clarke MJ, Gokaslan ZL, Sciubba DM. A Systematic Review of Clinical Outcomes for Patients diagnosed with Skin Cancer Spinal Metastases. Accepted to Congress of Neurological Surgeons 2015 Annual Meeting. New Orleans, LA. September 26-30, 2015.

Hoffberger J, Wemmer J, Elder B, Goodwin R, Kosztowski T, Rigamonti D. . “Post Lumbar Puncture Log for Patients with iNPH.”  5th Meeting of the International Society of Hydrocephalus and CSF Disorders in Athens Greece, June 29-July 2, 2013.

Elder B, Goodwin R, Kosztowski T, Moran D, Jusue-Torres I, Hoffberger J, Rigamonti D. ”Is Intervention in Asymptomatic Hydrocephalus Justifiable?” 5th Meeting of the International Society of Hydrocephalus and CSF Disorders in Athens Greece, June 29-July 2, 2013.

Elder B, Goodwin R, Kosztowski T, Pindrik J, Moran D, Jusue-Torres I, Hoffberger J, Rigamonti D. “ETV versus Ventricular Tap Test.” 5th Meeting of the International Society of Hydrocephalus and CSF Disorders in Athens Greece, June 29-July 2, 2013.

Jusue-Torres I, Moran D, Elder B, Pindrik J, Goodwin R, Kosztowski T, Hoffberger J, Rigamonti D. “Current Tests Fail to Identify Early idiopathic Normal Pressure Hydrocephalus.” 5th Meeting of the International Society of Hydrocephalus and CSF Disorders,  Athens Greece, June 29-July 2, 2013.  

Orkoulas-Razis D, Ward A, Kosztowski T, Elder B, Goodwin RC, Hoffberger J, Carson K, Rigamonti D. The use of CT MRI guidance is not beneficial in the insertion of the proximal shunt catheter. The 4th Meeting of the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders, Kyoto, Japan. October 19 to 22, 2012.

Hsu W, Mohyeldin A, Shah SR, Johson L, Sedora-RomanNI, Kosztowski T, Rhys CA, Awad O, McCarthy E, Loeb D, Wolinsky JP, Gokaslan ZL, Quinones-Hinojosa A.  Generation of Chordoma Cell Line, JHC7, and the Identification of Brachyury as a Novel Molecular Target.  AANS Aug  2011

Wesley Hsu; Ahmed Mohyeldin; Sagar R. Shah; Thomas Kosztowski; Lakesha johnson; Ola Awad; Neda I. Sedora-Roman; David Loeb; Edward McCarthy; Jean-Paul Wolinsky; Ziya L. Gokaslan; Alfredo Quinones-Hinojosa.   Identification of Cancer Stem Cells in Human Chordoma.  AANS Aug  2011

Mukherjee DM, Kosztowski TA, Zaidi HA, Chaichana K, Salvatori R, Chang D, Quinones-Hinojosa A. “Disparities in access to neuro-oncological care in the United States” Congress of Neurological Surgeons Annual Meeting—Top Ten Abstracts, New Orleans, LA, October 24, 2009.

Mukherjee DM, Kosztowski TA, de Almeida JP, Chang D, Brem H, Quinones-Hinojosa A. “Risk Factors for Inappropriate Hospital-to-Hospital Transfer of Brain Tumor Patients.” Congress of Neurological Surgeons Annual Meeting, New Orleans, LA, October 24, 2009.

Mukherjee DM, Kosztowski TA, de Almeida JP, Chang D, Brem H, Quinones-Hinojosa A. “Effect of Surgical Approach and Extent of Resection on Patient Outcomes Following Hypophysectomy for Sellar and Parasellar Tumors.”  Congress of Neurological Surgeons Annual Meeting, New Orleans, LA, October 24, 2009.

Mukherjee D, Zaidi HA,  Kosztowski TA, Chaichana KL, Salvatori R, Chang DC, Quinones-Hinojosa A.  “Worsening Racial Disparities in Access to Sellar and Parasellar Tumor Resection, 1988-2005” XIV World Congress of Neurological Surgery of the World Federation of Neurosurgical Societies (WFNS), 2009.

Schneider AM, Huang CR, Costello JF, Kosztowski TA, Quiñones-Hinojosa A, Burns KH, Boeke JD. L1 LINE human retrotransposon insertion site profiling in brain cancer. Federation of American Societies for Experimental Biology Conference. June 2009.

Kosztowski TA, Mukherjee D,  Zaidi HA, Jallo GI, Carson B, Chang DC, Quinones-Hinojosa A. “Disparities in access to pediatric neuro-oncological care in the United States.”  Johns Hopkins Medical Student Research Day. May 8, 2009.

Mukherjee D, Zaidi HA,  Kosztowski T, Chaichana KL, Salvatori R, Chang DC, Quinones-Hinojosa A.  “Predictors of Access to Pituitary Tumor Resection in the United States, 1988-2005” The Endocrine Society's 91st Annual Meeting, 2009.

Mukherjee D,  Zaidi HA,  Kosztowski T, Chaichana KL, Brem H, Chang DC, Quinones-Hinojosa A. “Disparities in access to neuro-oncological care over 17 years in the United States:  Are we worse off than before?”  The 3rd Annual Bayview Research Symposium, 2008.

Guerrero-Cazares H, Achanta P, Garzon-Muvdi T, Anghileri E, Kosztowski TA, Zaidi HA, Niranjan A, Martinez-Mejia S, Smith C, Vela G, Atri D, Quinones-Hinojosa A.  “Migration of Human Neural Stem Cells and Glioma-Derived Brain Tumor Stem Cells” The 3rd Annual Bayview Research Symposium, 2008.

Vick D, Hertig S, Tyler BM, Li KW, Renard V,  Kosztowski T, Legnani FG, Brem H, Olivi A. Local Delivery of Epirubicin for the Treatment of an Experimental Rodent Glioma. AANS/CNS Section on Tumors Seventh Biennial Satellite Symposium, Washington, DC, April 13-14, 2007.

Case Studies Presented by Thomas A Kosztowski, MD

Minimally Invasive Resection of an Intradural Spinal Tumor

Presented by: J. Ammerman MD, J. Wind MD, T. Kosztowski MD
A 38-year-old female presents with one-year history of left leg pain radiating from her buttock into the lateral aspect of the foot.

Financial Disclosures

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Author's Statement

I, the undersigned, declare that neither I nor members of my immediate family have a financial interests or affiliation with commercial companies whose products and / or services may be mentioned in the materials I have authored, edited or reviewed for presentation on Vertical Health, LLC’s websites.
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