Mark E. Oppenlander, MD's portrait
Mark E. Oppenlander, MD
Clinical Assistant Professor
Department of Neurosurgery
University of Michigan
Ann Arbor, MI

About Mark E. Oppenlander, MD

Mark Oppenlander, MD is a Clinical Assistant Professor, Department of Neurosurgery at the University of Michigan in Ann Arbor, MI.

Dr. Oppenlander attended the University of Michigan, where he graduated with Highest Distinction and a Bachelor of Science in Cellular and Molecular Biology. He went on to earn his Doctor of Medicine at the University of Michigan Medical School. In 2008, Dr. Oppenlander moved to Phoenix, Arizona where he completed a seven-year residency training program in Neurological Surgery at the Barrow Neurological Institute (BNI). He also spent time at Thomas Jefferson University in Philadelphia, where he obtained fellowship training in Complex Spine Surgery. In addition, Dr. Oppenlander was awarded the Royal College of Surgeons of Edinburgh Overseas Training Sponsorship, providing opportunity to travel to London, England for further fellowship training in Complex Spine Surgery and Spinal Oncology at the National Hospital for Neurology and Neurosurgery at Queen Square.

To date, Dr. Oppenlander has published over 70 peer-reviewed articles, book chapters, and abstracts, and participated in conferences at the state, national, and international level with multiple invited presentations. He is an active member of the Congress of Neurological Surgeons (CNS) and the American Association of Neurological Surgeons (AANS).

 

Publications

Peer-Reviewed Journals and Publications
1. Tözüm TF, Oppenlander ME, Koh-Paige AJ, Robins DM, McCauley LK. Effects of sex steroid receptor specificity in the regulation of skeletal metabolism. Calcif Tissue Int. 2004. Jul;75(1):60-70. PMID: 15037970.

2. Oppenlander ME, Orringer DA, La Marca F, McGillicuddy JE, Sullivan SE, Chandler WF, Park P. Dysphagia due to anterior cervical hyperosteophytosis. Surg Neurol. 2009.  Sep;72(3):266-70; discussion 270-1. Epub 2009 Jan 14. PMID: 19147185.

3. Oppenlander ME, Rekate HL. Use of adipose tissue to ease compatibility of a stylet with its sheath during ventriculoperitoneal shunt placement: technical note. Neurosurgery. 2010 Jun;66(6 Suppl Operative):333. PMID: 20489526.

4. Lochhead R, Abla A, Mitha A, Fusco D, Almefty K, Oppenlander ME, Albuquerque F. A history of the barrow neurological institute. World Neurosurg. 2010 Jul;74(1):71-80. PMID:21299987.

5. Oppenlander ME, Spetzler RF. Advances in spinal hemangioblastoma surgery. World Neurosurg. 2010 Jul;74(1):116-7. PMID: 21299999. Editorial.

6. Oppenlander ME, Kalani MYS, Dickman CA. Spinal and paraspinal giant cervical cavernous malformation with postpartum presentation: Case report. J Neurosurg Spine. 2012 May;16(5):447-51. PMID: 22360563.

7. Wilson DA, Nakaji P, Abla AA, Uschold TD, Fusco DJ, Oppenlander ME, Albuquerque FC,McDougall CG, Zabramski JM, Spetzler RF. A simple and quantitative method to predict symptomatic vasospasm after subarachnoid hemorrhage based on computed tomography:Beyond the fisher scale. Neurosurgery. 2012 Oct;71(4):869-76. PMID: 22801639.

8. Little AS, Oppenlander ME, Knecht L, Duick D, White WL. Early postoperative serum cortisol measurements guide management in a steroid-sparing protocol and predict need for long-term steroid replacement after resection of nonfunctioning pituitary adenomas. J Biosci Med. 2013 Feb;3(1):18-22. DOI: 10.5780/jbm2013.3.

9. Abla AA, Gandhoke G, Clark JC, Oppenlander ME, Velat GJ, Albuquerque FC, Zabramski JM, Nakaji P, Spetzler RF, Wanebo JE. Outcomes for Moyamoya Angiopathy with Comparison of Adult Indirect, Adult Direct, and Pediatric Bypass: 154 revascularization surgeries in 140 affected hemispheres. Neurosurgery. 2013 Sep;73(3):430-9. PMID:23756739.

10. Oppenlander ME, Clark JC, Kalyvas J, Dickman CA. Surgical management and clinical outcomes of multiple-level symptomatic herniated thoracic discs. J Neurosurg Spine. 2013 Dec;19(6):774-83. PMID: 24116677.

11. Oppenlander ME, Kalyvas J, Sonntag VKH, Theodore N. Technical advances in pediatric craniovertebral junction surgery. Adv Tech Stand Neurosurg. 2014;40:201-13. PMID:24265047.

12. Oppenlander ME, Clark JC, Sonntag VKH, Theodore N. Pediatric craniovertebral junction trauma. Adv Tech Stand Neurosurg. 2014;40:333-53. PMID: 24265053.

13. Snyder LA, Wolf A, Oppenlander ME, Bina R, Wilson J, Ashby L, Brachman D, Coons SW, Spetzler RF, Sanai N. The impact of extent of resection on malignant transformation of pure oligodendrogliomas. J Neurosurg. 2014 Feb;120(2):309-14. PMID: 24313617.

14. Oppenlander ME, Maulucci CM, Ghobrial GM, Harrop JS. Research in spinal surgery: Evaluation and practice of evidence-based medicine. World J Orthop. 2014 April 18;5(2): 89-93. PMID: 24829870.

15. Ghobrial GM, Thakkar V, Andrews E, Lang M, Chitale A, Oppenlander ME, Maulucci CM, Sharan AD, Heller J, Harrop JS, Jallo J, Prasad S. Intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends. Spine (Phila Pa 1976). 2014 Apr 1;39(7):550-5. PMID: 24480966.

16. Oppenlander ME, Wolf AB, Snyder LA, Bina R, Wilson JR, Coons SW, Spetzler RF, Sanai N. An extent of resection threshold for recurrent glioblastoma and its risk for neurological morbidity. J Neurosurg. 2014 Apr;120(4):846-53. PMID: 24484232.

17. Oppenlander ME, Bina R, Snyder LA, Dickman CA. Intravertebral polymethylmethacrylate augmentation of anterior cervical discectomy fusion and plating in the setting of osteoporosis. J Spinal Disord Tech. 2014 May;27(3):185-8. PMID: 24945297.

18. Oppenlander ME, Chowdhry SA, Merkl B, Hattendorf GM, Nakaji P, Spetzler RF. Robotic auto-positioning of the operating microscope. Neurosurgery. 2014 Jun;10 Suppl 2:214-9. PMID: 24335818.

19. Ghobrial GM, Oppenlander ME, Maulucci CM, Viereck M, Prasad S, Sharan AD, Harrop JS. Management of asymptomatic cervical spinal stenosis in the setting of symptomatic tandem lumbar stenosis: a review. Clin Neurol Neurosurg. 2014 Sep;124:114-8. PMID: 25036872.

20. Maulucci CM, Ghobrial GM, Oppenlander ME, Flanders AE, Vaccaro AR, Harrop JS. Arachnoiditis ossificans: Clinical series and review of the literature. Clin Neurol Neurosurg. 2014 Sep;124:16-20. PMID: 24999276.

21. Oppenlander ME, Maulucci CM, Ghobrial GM, Evans NR 3rd, Harrop JS, Prasad SK. En bloc resection of upper thoracic chordoma via a combined simultaneous anterolateral thoracoscopic and posterior approach. Neurosurgery. 2014 Sep;10 Suppl 3:380-6; discussion 386. PMID: 24739365.

22. Ghobrial GM, Thakkar V, Singhal S, Oppenlander ME, Maulucci CM, Harrop JS, Jallo J, Prasad S, Saulino M, Sharan AD. Efficacy of intraoperative vancomycin powder use in intrathecal baclofen pump implantation procedures: Single institutional series in a high risk population. J Clin Neurosci. 2014 Oct;21(10):1786-9. PMID: 24938386.

23. Safavi-Abbasi S, Sun H, Oppenlander ME, Nakaji P, Kalani MYS, Zabramski JM, and Spetzler RF. Repair of intraoperative aneurysm neck tear utilizing the cotton-clipping technique. Neurosurg Focus. 2015 Jan;38(VideoSuppl1):Video14. PMID: 25554836.

24. Kalani MYS, Oppenlander ME, Levitt M, Safavi-Abbasi S, Spetzler RF, and Zabramski JM. Microsurgical clipping of an unruptured basilar apex aneurysm. Neurosurg Focus. 2015 Jan; 38(VideoSuppl1):Video10. PMID: 25554832.

25. Oppenlander ME, Clark JC, Kalyvas J, Dickman CA. Indications and techniques for spinal instrumentation in thoracic disc surgery. J Spinal Disord Tech. 2014 Jun 5. [Epub ahead of print] PMID: 24905502.

26. Oppenlander ME, Hsu FD, Bolton P, Theodore N. Catastrophic neurological complications of emergent endotracheal intubation: Report of two cases. J Neurosurg Spine. 2015 Feb 27:1-5. [Epub ahead of print] PMID: 25723119.

Non Peer-Reviewed Publications:
27. Ghobrial GM, Oppenlander ME, Maulucci CM, Harrop JS. Osteoporosis: Morbidity, perioperative implications, and a review of the management in spinal surgery. JHN Journal. 2013 Dec;8(2):15-18.

28. Maulucci CM, Oppenlander ME, Harrop JS. Parsonage-Turner syndrome: A forgotten diagnosis. CNS Quarterly. 2014 Winter;15(1):25.

29. Oppenlander ME, Serruya M, Harrop JS. Optogenetics: A wide therapeutic potential. CNS Quarterly. 2014 Winter;15(1):26.

30. Clark JC, Oppenlander ME, Dickman CA. Thoracoscopy: A minimally invasive approach to the anterior thoracic spine. Barrow Quarterly. 26(1). In press.

Book Chapters:
31. Oppenlander ME, Wanebo J. Moyamoya disease. In Aminoff MJ, Daroff RB (eds): Encyclopedia of Neurological Sciences, 2nd ed., Oxford: Elsevier, 2014.

32. Oppenlander ME, Porter RW. Stereotactic radiosurgery, gamma knife and cyberknife. In Aminoff MJ, Daroff RB (eds): Encyclopedia of Neurological Sciences, 2nd ed., Oxford: Elsevier, 2014.

33. Maulucci CM, Oppenlander ME, Heller JE. Posterior fusion techniques for lumbar degenerative scoliosis. In Harrop JS, Vaccaro AR (eds): Adult Degenerative Scoliosis - Coronal and sagittal deformities treatment and management. Chap 12, pp 102-105. London: Jaypee Brothers Medical Publishers, 2015.

34. Kalb S, Perez-Orribo L, Oppenlander ME, Kalani MYS, Spetzler RF: Aneurysms of spinal arteries. In Kalani MYS, Nakaji P, Spetzler RF (eds): Neurovascular Surgery, 2nd ed., New York: Thieme, Expected publication: May 29, 2015.

35. Maulucci CM, Oppenlander ME, Ghobrial GM, Harrop JS. Thoracolumbar spine injuries. Harbaugh RE, Berger MS, Couldwell WT, and Shaffrey C (eds): Neurosurgery Knowledge Update, New York: Thieme, Expected publication: June 12, 2015.

36. Oppenlander ME, Maulucci CM, Hann S, Harrop JS. Thoracolumbar biomechanics. In Hak D, Hao J, Mauffrey C (eds): Guke Pindao - The Orthopedic Channel, e-book (gukepindao.com).

37. Hann S, Oppenlander ME, Maulucci CM, Ghobrial GM, Harrop JS. Neuromonitoring modalities in spinal surgery. In Hak D, Hao J, Mauffrey C (eds): Guke Pindao - The Orthopedic Channel, e-book (gukepindao.com).

38. Maulucci CM, Oppenlander ME, Hann S, Harrop JS. Cervical spine biomechanics. In Hak D, Hao J, Mauffrey C (eds): Guke Pindao - The Orthopedic Channel, e-book (gukepindao.com).

39. Oppenlander ME and Harrop JS. Thoracic disc herniation. In Vaccaro AR, Prasad SK, Rihn J, Wang M (eds): Clinical Decision Support System on Spine Surgery, Decision Support in Medicine, LLC. https://www.decisionsupportinmedicine.com/ (in press).

40. Ghobrial GM, Oppenlander ME, Harrop JS. Management of malignant spinal tumors. In Austin M, Klein G (eds): Recent Trends in Orthopedic Oncology, London: Jaypee Brothers Medical Publishers (in press).

41. Oppenlander ME, Maulucci CM, Ghobrial GM, Prasad SK. Robotic applications in spinal surgery. In Vaccaro AR, Albert TJ (eds): Spine Surgery: Tricks of the Trade, 3rd ed., New York: Thieme (in press).

42. Ghobrial GM, Oppenlander ME, Prasad SK. Spinal radiosurgery for metastases. In Vaccaro AR, Albert TJ (eds): Spine Surgery: Tricks of the Trade, 3rd ed., New York: Thieme (in press).

43. Oppenlander ME, Maulucci CM, Harrop JS. Transthoracic and transabdominal approaches to the spine. In Kumar M, Kofke A, Levine J (eds): Neurocritical Care Management of the Neurosurgical Patient, Philadelphia: Elsevier (in press).

Other Media:
44. Oppenlander ME, Harrop JS. Intradural calcified thoracic meningioma. SpineUniverse Case Study Library. http://www.spineuniverse.com/professional/case-studies/oppenlander/intradural-calcified-thoracic-meningioma. Published and accessed November 1, 2013.

45. Ghobrial GM, Oppenlander ME, Hilibrand AS, Prasad SK, Harrop JS. Open cervical reduction techniques. In Landriel F, Vecchi E, Gonzalvo A (eds): Video Atlas of Spine Surgical Techniques, e-book, 2014.

Comments:
46. Oppenlander ME, Nakaji P. Comments on: Gephart MH, Derstine P, Oyesiku NM, Grady MS, Burchiel K, Batjer HH, Popp AJ, Barbaro NM. Resident away rotations allow adaptive neurosurgical training. Neurosurgery. 2015 Apr;76(4):421-6. PMID: 25635889.

47. Oppenlander ME, Spetzler RF. Comments on: Comparison of outcome between surgical and conservative management of symptomatic spinal cord cavernous malformations.Neurosurgery. 2015 in press: NEU-D-15-00499R2.

Abstracts:
48. Tozum TF, Oppenlander ME, Chen C, Robins DM, McCauley LK. Impact of estrogen and androgen receptors on skeletal metabolism. The American Society for Bone and Mineral Research 24th Annual Meeting. San Antonio, TX. September 20-24, 2002.

49. Oppenlander ME, Tozum TF, Robins DM, McCauley LK. Effects of estrogen receptor-alpha and androgen receptor in skeletal metabolism. Undergraduate Research Opportunity Program Spring Symposium. Ann Arbor, MI. 2002.

50. McCauley LK, Brogley M, Tozum TF, Patel K, Oppenlander ME, Scheller A, Robins DM. Analysis of androgen and estrogen action in mice deficient for both AR and ER alpha. The Endocrine Society 84th Annual Meeting. San Francisco, CA. June 19-22, 2002.

51. Oppenlander ME, Burmeister M, Marchini A, Hristov G, Rappold G. The homeodomain protein SHOX: Growth, Leri-Weill, and Turner syndromes. 51st Annual Student Biomedical Research Forum. Ann Arbor, MI. 2005.

52. Orringer DA, Oppenlander ME, La Marca F, McGillicuddy JE, Sullivan SE, Chandler WF, Park P. Dysphagia due to anterior cervical hyperosteophytosis. University of Michigan Neuroscience Day. Ann Arbor, MI. May, 2007.

53. Oppenlander ME, Little AS, White WL. Early postoperative cortisol level as a guide to steroid supplementation after pituitary adenoma surgery. The International Society of Pituitary Surgeons. Sonoma, CA. October 14-16, 2010.

54. Oppenlander ME, Sanai N. An extent of resection threshold for recurrent glioblastomas: Preliminary results. Arizona Neurosurgical Society. Tucson, AZ. October 29, 2011.

55. Oppenlander ME, Wolf AB, Nakaji P, Porter R, Smith KA, Spetzler RF, Sanai N. The value of extent of resection in recurrent glioblastoma. Society for Neuro Oncology 16th Annual Scientific Meeting. Anaheim, CA. November 17-20, 2011.

56. Oppenlander ME, Wolf AB, Nakaji P, Porter R, Smith KA, Spetzler RF, Sanai N. An extent of resection threshold for recurrent glioblastomas. American Association of Neurological Surgeons (AANS) 80th Annual Scientific Meeting. Miami, FL. April 14-18, 2012.

57. Oppenlander ME, Hsu FD, Theodore N. Catastrophic neurologic complications of emergent endotracheal intubation. American Association of Neurological Surgeons (AANS) 80th Annual Scientific Meeting. Miami, FL. April 14-18, 2012.

58. Oppenlander ME, Clark JC, Dickman CA. Herniated thoracic disc surgery. Arizona Neurosurgical Society. Tucson, AZ. November 3, 2012.

59. Abla AA, Gandhoke G, Clark JC, Oppenlander ME, Velat GJ, Albuquerque FC, Zabramski JM, Nakaji P, Spetzler RF, Wanebo JE. Outcomes for Moyamoya Angiopathy with Comparison of Adult Indirect, Adult Direct, and Pediatric Bypass: 154 revascularization surgeries in 140 affected hemispheres. The 3rd SNIS International Endovascular Stroke Conference and the CNS/AANS Joint Cerebrovascular Section Annual Meeting. Honolulu, HA. February 4-5, 2013.

60. Kalyvas J, Kalb S, Oppenlander ME, Kakarla UK, Hsu FD, Theodore N. Posterior vertebral column subtraction osteotomy for the treatment of tethered cord syndrome: A prospective outcome study. Global Spine Congress. Hong Kong. April 4-6, 2013.

61. Oppenlander ME, Clark JC, Kalyvas J, Dickman CA. Surgical management and clinical outcomes of multiple-level symptomatic herniated thoracic discs. Global Spine Congress. Hong Kong. April 4-6, 2013.

62. Kalyvas J, Kalb S, Oppenlander ME, Kakarla U, Hsu Forrest, Theodore N. Posterior vertebral column subtraction osteotomy for the treatment of tethered cord syndrome: A prospective outcome study. American Association of Neurological Surgeons (AANS) 81st Annual Scientific Meeting. New Orleans, LA. April 27-May 1, 2013.

63. Clark JC, Oppenlander ME, Dickman CA. Anterior approaches for symptomatic central herniated thoracic discs. American Association of Neurological Surgeons (AANS) 81st Annual Scientific Meeting. New Orleans, LA. April 27-May 1, 2013.

64. Kalyvas J, Elhadi A, Oppenlander ME, Theodore N. Utility of ultrasonic osteotomy compared to conventional techniques for cervical laminectomy in patients with cervical spondylotic myelopathy. American Association of Neurological Surgeons (AANS) 81st Annual Scientific Meeting. New Orleans, LA. April 27-May 1, 2013.

65. Oppenlander ME, Clark JC, Kalyvas J, Dickman CA. Indications for spinal instrumentation in thoracic disc surgery. American Association of Neurological Surgeons (AANS) 81st Annual Scientific Meeting. New Orleans, LA. April 27-May 1, 2013.

66. Theodore N, Kakarla K, Kalyvas J, Kalb S, Oppenlander ME. Posterior vertebral column subtraction osteotomy for the treatment of tethered cord syndrome: a prospective outcome study. The American Academy of Neurological Surgeons 75th Annual Meeting. Newport Beach, CA. September 25-28, 2013.

67. Clark JC, Oppenlander ME, Dickman CA. Anterior approaches for symptomatic central herniated thoracic discs. Oral Poster Presentation. AANS/CNS Section on Disorders of the Spine and Peripheral Nerves. Orlando, FL. March 5-8, 2014.

68. Ghobrial GM, Thakkar V, Andrews E, Lang M, Chitale A, Oppenlander ME, Maulucci CM, Sharan AD, Heller J, Harrop JS, Jallo J, Prasad S. Intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends. Oral Poster Presentation. AANS/ CNS Section on Disorders of the Spine and Peripheral Nerves. Orlando, FL. March 5-8, 2014.

69. Oppenlander ME, Harrop JS, Prasad S. Occipitocervical fusion: does posterior occipitocervical angle predict reoperation? Arizona Neurosurgical Society. Tucson, AZ. November 22, 2014.

70. Haylock-Vize P, Oppenlander ME, Choi D. Tomita en-bloc resection of aggressive vertebral haemangiomas - A Retrospective Case Series. Society of British Neurological Surgeons. Southampton, England. April 23, 2015.

71. Bohl M, Clark JC, Oppenlander ME, Meeusen AJ, Budde A, Porter RW, Spetzler RF. The Barrow Randomized OR Traffic (BRITE) Trial: The Effect of OR Traffic on Infection Rates. Congress of Neurological Surgeons. New Orleans, LA. September 26-30, 2015.

Case Studies Presented by Mark E. Oppenlander, MD

Lumbar Adjacent Segment Disease

Presented by: M. Oppenlander MD
A 72-year-old woman presents with low back pain and leg pain. Ten years ago, she underwent L4-S1 posterior decompression with instrumentation and fusion. Presently, her back pain is in the mid-lumbar region and is exacerbated with activity and improves when supine.

Intradural Calcified Thoracic Meningioma

Presented by: M. Oppenlander MD, J. Harrop MD, FACS
This 78-year-old woman presents with progressive gait difficulty. She went from independent ambulation to requiring the use of a walker, and now has difficulty even with standing. Extensive workup eventually found an intradural lesion.

Financial Disclosures

SpineUniverse, a Vertical Health, LLC website, is committed to ensuring that the medical information it presents is accurate, balanced, objective, and trustworthy. 

To help achieve this goal, SpineUniverse requires all authors, editors, and reviewers to disclose any financial relationships or affiliations they have with companies whose products or services may be mentioned in the content they author, edit, or review.

The intent of this policy is to identify any perceived, potential, or real conflicts of interest so that readers can make their own judgments about the value of information being presented.

Author's Statement

I, the undersigned, declare that neither I nor members of my immediate family have a financial interests or affiliation with commercial companies whose products and / or services may be mentioned in the materials I have authored, edited or reviewed for presentation on Vertical Health, LLC’s websites.
SHOW MAIN MENU
SHOW SUB MENU
Cancel
Delete