Celebrex: Introduction
Celecoxib [Oral]
Brand
Name: Celebrex
Generic Name: Celecoxib [Oral]
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Generic Name: Celecoxib [Oral]
| Pronunciation: | sel-e-COX-ib |
| Drug class: | Analgesic [Nonsteroidal Anti-Inflammatory Drug (NSAID)]; COX-2 Inhibitor |
| Generic available? | No |
| Controlled substance? | No |
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Celecoxib belongs to a class of nonsteroidal anti-inflammatory drugs (NSAIDs) called cyclooxygenase-2 (COX-2) inhibitors. It is used to relieve the pain and inflammation associated with rheumatoid arthritis and osteoarthritis. Celecoxib differs from the other nonsteroidal anti-inflammatory inhibitors in that it selectively inhibits the COX-2. In contrast, other NSAIDs inhibit both COX-1 and COX-2. COX-2 is thought to be responsible for making inflammatory prostaglandins while COX-1 makes prostaglandins that are beneficial to kidney and stomach function. The advantage of this specificity is that celecoxib does not interfere with the cyclooxygenase that produces beneficial prostaglandins, making it less likely to cause gastrointestinal side effects. |
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Updated on: 02/01/10






