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 Chiropractic and Back Pain: Clinical Trial Results

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9. What has scientific research found out about whether chiropractic works for low back pain?
For this report, the results of individual clinical trials and reviews of groups of clinical trials were examined. Sources were drawn from the National Library of Medicine's PubMed database; were published in English; and studied chiropractic techniques that were identified as such (e.g., "chiropractic manipulation") rather than some other forms of "manipulation" or "spinal manipulation therapy"--which, as noted above, may be delivered by certain other health care providers.

So far, the scientific research on chiropractic and low back pain has focused on if, and how well, chiropractic care helps in relieving pain and other symptoms that people have with low back pain. This research often compares chiropractic to other treatments.

Research studies
Appendix I gives detailed findings from seven controlled clinical trials and one prospective observational study of chiropractic treatment for low back pain published between January 1994 and June 2003.

• Summary of the research findings
The studies all found at least some benefit to the participants from chiropractic treatment. However, in six of the eight studies, chiropractic and conventional treatments were found to be similar in effectiveness.(22,25-29) One trial found greater improvement in the chiropractic group than in groups receiving either sham manipulation or back school.30. Another trial found treatment at a chiropractic clinic to be more effective than outpatient hospital treatment.(31)

General reviews, systematic reviews, and meta-analyses
Appendix II lists three reviews of clinical trials on chiropractic treatment for back pain, published between October 1996 and June 2003.

• Summary of the research findings
Overall, the evidence was seen as weak and less than convincing for the effectiveness of chiropractic for back pain. Specifically, the 1996 systematic review reported that there were major quality problems in the studies analyzed; for example, statistics could not be effectively combined because of missing and poor-quality data. The review concludes that the data "did not provide convincing evidence for the effectiveness of chiropractic.(32) The 2003 general review states that since the 1996 systematic review, emerging trial data "have not tended to be encouraging…. The effectiveness of chiropractic spinal manipulation for back pain is thus at best uncertain.(33) The 2003 meta-analysis found spinal manipulation to be more effective than sham therapy but no more or no less effective than other treatments.(10)

Several other points are helpful to keep in mind about the research findings. Many clinical trials of chiropractic analyze the effects of chiropractic manipulation alone, but chiropractic practice includes more than manipulation (see Question 5).(34) Results of a trial performed in one setting (such as a managed care organization or a chiropractic college) may not completely apply in other settings.(29,35) And, researchers have observed that the placebo effect may be at work in chiropractic care,(34) as in other forms of health care.

Note: This fact sheet often uses the term "adjustment" to refer to chiropractic manipulation. In Question 9 and Appendices I and II, "manipulation" is used where it is used in the source(s) on chiropractic being discussed.

10. Are there scientific controversies associated with chiropractic?
Yes, there are scientific controversies about chiropractic, both inside and outside the profession. For example, within the profession, there have been disagreements about the use of physical therapy techniques, which techniques are most appropriate for certain conditions, and the concept of subluxations. Outside views have questioned the effectiveness of chiropractic treatments, their scientific basis, and the potential risks in subsets of patients (for example, the risks of certain types of adjustments to patients with osteoporosis or risk factors for osteoporosis, compared to patients with healthier bone structures.(33,36)

Research studies on chiropractic are ongoing. The results are expected to expand scientific understanding of chiropractic. A key area of research is the basic science of what happens in the body (including its cells and nerves) when specific chiropractic treatments are given.

11. Is NCCAM funding research on chiropractic?
Yes. For example, recent projects supported by NCCAM include:

• Comparing conventional medical care for acute back pain with an "expanded benefits" package (consisting of conventional care plus a choice of chiropractic, massage, or acupuncture)

• Finding out what happens (through measurement) in the lumbar portion of the spine after chiropractic positioning and adjustment

• Evaluating the effects of the speed of spinal adjustment on muscles and nerves * Studying the effectiveness of chiropractic adjustment for a variety of conditions, including neck pain, chronic pelvic pain, and temporomandibular disorders (TMD) in the jaw

National Center for Complementary and Alternative Medicine(NCCAM)
http://nccam.nih.gov/health/chiropractic/index.htm
National Institutes of Health, U.S. Department of Health and Human Services
NCCAM Publication No. D196 November 2003

Continue this article...


Clinical Trials from A to Z - Key Questions
Developing the Chronic Pain Picture and Chiropractic Care
Chiropractic Philosophy
About Chiropractic and Low Back Pain: Definitions
About Chiropractic and Low Back Pain: References and Appendixes
What Kind of Training Do Chiropractors Receive?
Article written 11/01/2003
Published online 12/29/2005
Last updated 02/19/2007

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