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 Arthrotec: Introduction

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Diclofenac Sodium with Misoprostol  [Oral]

Brand Name: Arthrotec
Other Brand Names:
Arthrotec 50; Arthrotec 75
Generic Name: Diclofenac Sodium with Misoprostol [Oral]

Pronunciation: di-KLOH-fen-ak SOH-dee-um with mi-soh-PROH-stohl
Drug class: Analgesic [Nonsteroidal Anti-Inflammatory Drug (NSAID)]/Anti-Ulcer; Anti-Rheumatic; Antiarthritic
Generic available? No
Controlled substance? No

Oral diclofenac sodium with misoprostol is combination product containing a nonsteroidal anti-inflammatory drug (NSAID) and a cytoprotective (stomach protecting) agent, respectively. It is used as an alternative to other NSAIDs to reduce inflammation and pain associated with osteoarthritis and rheumatoid arthritis, without causing unwanted side effects, such as stomach irritation and ulcers.

Diclofenac with misoprostol has anti-inflammatory, fever-reducing, and pain-relieving properties. Diclofenac works by inhibiting cyclooxygenase, an enzyme responsible for making prostaglandins which are mediators of inflammation. Misoprostol, a synthetic prostaglandin E1 analogue, inhibits gastric acid secretion and reduces the risk of gastrointestinal irritation and ulcers.

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Article written 00/00/0000
Published online 00/00/0000
Last updated 08/08/2007

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