Lumbar Discectomy and Anular Repair
Patient Guide

Complete Anular Repair Bibliography

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Table of Contents

  1. Anulex Technology Products: Conference Presentations
    A.  Xclose Tissue Repair System
    B.  Economics
  2. Anulex Technology Products
    C.  Book Chapters
    D.  Manuscripts and White Papers
  3. Other Literature
    E. Book Chapters on Anular Repair
    F. Basic Science of Discectomy and Anular Repair
    G. Clinical Science of Discectomy and Anular Repair
    H. Spine Patient Outcome Research Trial (SPORT) Disc Herniation Trial
    I. Economics

I. Anulex Technologies Products: Conference Presentations

Xclose™ Tissue Repair System:

  1. Bourgeault C, Beaubien BP, Freeman AL, Bentley I, Houfburg R, Griffith SL.  Biomechanical assessment of anulus fibrosus repair with suture-tethered tissue anchors. Proceedings of the Seventh Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS7), Berlin, Germany 2007.
     
  2. Bajares G, Perez A, Rodriquez R. A pilot study evaluating a novel device that re-approximates the anulus fibrosus following a discectomy procedure. Proceedings of the Seventh Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS7), Berlin, Germany 2007  and Proceedings of 22nd North American Spine Society (NASS), The Spine Journal 7:118S, 2007.
     
  3. Guyer R, Blumenthal S, Sachs B, Hochschuler S,  Zigler J, et al. (On behalf of Anulex Anular Repair Clinical Investigators).  A clinical evaluation of anular repair post lumbar discectomy.  Proceedings of the Eighth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS8), Miami, FL 2008. 
     
  4. Bajares G, Perez A, Rodriquez R.  One-year follow-up of discectomy patients who received a novel device that re-approximates the anulus fibrosus.  Proceedings of the Eighth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS8), Miami, FL 2008.
     
  5. Myers ME, Griffith SL, Snider J.  MRI Analysis of disc morphology in post-microdiscectomy asymptomatic patients with anular repair.  Twenty-fifth Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves.  Phoenix, AZ, March 2009.
     
  6. Bartlett A, Wales L, Houfburg R, Griffith SL.  Anular repair is affected by quantity but not configuration of devices: a laboratory simulation.  Twenty-fifth Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves.  Phoenix, AZ, March 2009.
     
  7. Messer JM, Blatt GL.  Intra-operative analysis of anular competence as related to anular repair in primary lumbar discectomy patients.  Twenty-fifth Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves.  Phoenix, AZ, March 2009.
     
  8. Inoue N, Espinoza-Orias AA, Natarajan R, An HS, Kode S, Gudipally M, Takigawa T, Griffith SL.  Biomechanical evaluation of the lumbar spine after anular repair. Proceedings of the Ninth Global Symposium on Motion Preservation Technology. Spine Arthroplasty Society (SAS9), London, England 2009.
     
  9. Blatt G, Amundson GM, Bailey AS, Griffith SL.  Intraoperative analysis of anular competence as related to anular repair in primary lumbar discectomy patients.  Proceedings of the Ninth Global Symposium on Motion Preservation Technology. Spine Arthroplasty Society (SAS9), London, England 2009.
     
  10. Guyer RD, Blumenthal S, Sachs B, Hochschuler S, Amundson G, Bailey A, Blatt G. The effect of compensation status on surgical outcomes in patients undergoing lumbar discectomy with subsequent anular repair.  Proceedings of the Ninth Global Symposium on Motion Preservation Technology.  Spine Arthroplasty Society (SAS9), London, England, 2009.
     
  11. Myers ME, Griffith SL, Snider J.  MRI Analysis of disc morphology in post-microdiscectomy asymptomatic patients with anular repair. Proceedings of the Ninth Global Symposium on Motion Preservation Technology (SAS9). London, England, April 2009.
     
  12. Bartlett A, Wales L, Houfburg R, Griffith SL.  Anular repair is effected by quantity but not configuration of devices: A laboratory simulation.   Proceedings of the Ninth Global Symposium on Motion Preservation Technology (SAS9). London, England, April 2009.
     
  13. Hartman L, Griffith SL, Melone B, Melone D.  Surgical outcome of lumbar microdiscectomy with emphasis on the benefit of anular repair techniques.  2009 Annual Meeting of the Congress of Neurological Surgeons (CNS). New Orleans, LA, October 2009.
     
  14. Blumenthal S (On behalf of the clinical investigators who contributed cases to this analysis).  Anulus Repair: Randomized trial with Xclose.  XVIth Brussels International Spine Symposium.  Brussels, Belgium, November 20, 2009.
     
  15. Bailey A, Messer J.  Prospective, randomized controlled study of repairing the anulus fibrosus after lumbar discectomy: A single surgeon’s experience.  Twenty-sixth Annual Meeting of the AANS/CNS Section of Disorders of the Spine and Peripheral Nerves. February 18, 2010.
     
  16. Guyot L, Griffith SL.  Re-operation rates after microdiscectomy with and without anular repair.  Twenty-sixth Annual Meeting of the AANS/CNS Section of Disorders of the Spine and Peripheral Nerves. February 18, 2010.
     
  17. Rich K (On behalf of the clinical investigators who contributed cases to this analysis).  Preliminary observations from an ongoing prospective randomized controlled clinical trial.  Sixty-first Southern Neurosurgical Society (SNS). Boca Raton, FL, February 2010.
     
  18. Guyer R, Blumenthal S, Bailey A, Amundson G, Chedid M, Gerdes JS, Messer J, Griffith SL. Anulex Anular Repair Clinical Investigators Group Preliminary Observations from a Prospective, Multi-center, Randomized, Controlled Clinical Trial Evaluating Anular Repair after Lumbar Discectomy.  Tenth Annual Global Symposium on Motion Preservation Technology (SAS10). New Orleans, LA, April 2010.
     
  19. Bailey A, Messer J, Griffith SL.  Prospective, randomized controlled study of repairing the anulus fibrosus after lumbar discectomy: A single surgeon’s experience.  Tenth Annual Global Symposium on Motion Preservation Technology (SAS10). New Orleans, LA, April 2010.
     
  20. Guyot L, Griffith SL.  Re-operation rates after microdiscectomy with and without anular repair.  Tenth Annual Global Symposium on Motion Preservation Technology (SAS10). New Orleans, LA, April 2010.
     
  21. Araghi A, Sugden C, Griffith SL.  The effect of anular repair on sciatica patients receiving a micro-discectomy procedure.  Tenth Annual Global Symposium on Motion Preservation Technology (SAS10). New Orleans, LA, April 2010.

B.  Economics

  1. Cauthen J, Sherman J, Griffith SL.  Economic impact of improving outcomes of lumbar discectomy.  Twenty-third Annual Meeting of the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves. Phoenix, AZ, March 2007.
  2. Sherman J, Cauthen J, Griffith SL.  Economic advantage to repairing the anulus fibrosus following discectomy.  Proceedings of the Seventh Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS7). Berlin, Germany 2007.
  1. Guyer RD, Blumenthal S, Sachs B, Hochschuler S, Amundson G, Bailey A, Blatt G. The effect of compensation status on surgical outcomes in patients undergoing lumbar discectomy with subsequent anular repair.  Proceedings of the Ninth Global Symposium on Motion Preservation Technology.  Spine Arthroplasty Society (SAS9). London, England, 2009.

 II.  Anulex Technology Products

C. Book Chapters

  1. Cauthen JC, Sherman J, Davis R, Peppelman W, Yonemura K, Griffith SL.  Repair of the Anulus Fibrosus (Anuloplasty) after Lumbar Discectomy.  Chapter 15 (pp 283-300), In: Non-Fusion Techniques for the Spine: Motion Preservation and Balance.  Maxwell JH, Welch W, Griffith SL, Editors.  St. Louis, MO: Quality Medical Publishing Inc, 2006.
     
  2. Yonemura K, Sherman J, Peppelman W, Griffith SL, Davis R, Cauthen JC.  Improving the Outcome of Discectomy with Specific Attention to the Anulus Fibrosus.    Chapter 5 (pp 59-80) In: Innovations is Spinal Reconstruction- Clinical Examples of Basic Science, Biomechanics, and Engineering.  Lewandrowski K, Yaszemski M, Kalfas IH, Park P, McLain RF, Trantolo DJ, Editors.   New York, NY: Informa Healthcare USA, 2007.
     
  3. Griffith SL, Davis RJ, Hutton WC. Repair of the Anulus Fibrosus of the Lumbar Disc.  Chapter 12 (pp 41- 48), In: Nucleus Arthroplasty Technology in Spinal Care: Volume II- Biomechanics & Development.  Davis R, Cammisa FP, Girardi FP, Hutton WC, Editors.  Bloomington, MN: Raymedica Co, (www.nucleusarthroplasty.com) 2007.
     
  4. Cauthen JC and Griffith SL.  Repair and Reconstruction of the Anulus Fibrosus with the Inclose™ Surgical Mesh System. Chapter 81 (pp 623- 628), In: Motion Preservation Surgery of the Spine-Advanced Techniques and Controversies.  Yue JJ, Bertagnoli R, McAfee PC, An H, Editors.  Philadelphia, PA: Elsevier, 2008.

D.  Manuscripts and White Papers

  1. Bartlett A, Wales L, Houfburg R, Griffith SL.  Optimizing the effectiveness of anulus fibrosus repair: A laboratory bench model.  Anulex White Paper, 2009.
     
  2. Sherman J, Cauthen J, Schoenberg D, Burns M, Reaven NL, Griffith SL.  Economic impact of improving outcomes of lumbar discectomy.  The Spine Journal, 2010; 10(2):108-116.
  3. Kode S, Gudipally M, Espinoza-Orias AA, Griffith SL, Inoue N.  Biomechanical evaluation of anular repair.  Submitted to the SAS Journal, September, 2009.
     
  4. Bartlett A, Wales L, Houfburg R, Griffith SL.  Optimizing the effectiveness of anulus fibrosus repair: A laboratory bench model.  submitted to Spine, September, 2009.
     
  5. Bailey A, Amundson G, Blumenthal S, Chedid M, Guyer R, Gerdes J, Messer J, Griffith SL.  Prospective multi-center randomized controlled study of anular repair in lumbar discectomy: Preliminary observations. Submitted to The Spine Journal, February, 2010.
     
  6. Cunningham BC, Hu N, Matthees EJ, Houfburg RL, Griffith SL, McAfee PC.  Multidirectional flexibility properties of the lumbar spine following implantation of anular repair mesh: an in-vitro cadaveric model.  In preparation.

III.  Other Literature

E.  Book Chapters on Anular Repair

  1. Cauthen JC.  Microsurgical anular reconstruction (anuloplasty) following lumbar microdiscectomy.  Chapter 11 (pp 155- 177).  In: Spinal Arthoplasty-A New Era in Spine Care.  Guyer RD, Zigler JE, Editors.  St Louis, MO: Quality Medical Publishing, 2005.
     
  2. Wang MY.  Indications and techniques in anuloplasty.  Chapter 47 (pp 375- 379) In: Dynamic Reconstruction of the Spine.  Kim DH, Cammisa FP, Fessler RG, Editors.  New York, NY: Thieme Medical Publishers, 2006.
     
  3. Einhorn J, Yeh O, Lambrecht G.  The Intrinsic Therapeutics Barricaid Device.  Chapter 82 (pp 629- 6636), In: Motion Preservation Surgery of the Spine- Advanced Techniques and Controversies.  Yue JJ, Bertagnoli R, McAfee PC, An H, Editors.  Philadelphia, PA: Elsevier, 2008.

F.  Basic Science of Discectomy and Anular Repair

  1. Ahlgren BD, Vasava A, Browser RS, Lydon C, Herkowitz HN, Panjabi MM.  Anular incision technique on the strength and multidirectional flexibility of the healing of the intervertebral disc.  Spine 19:948-954, 1994.
     
  2. Ahlgren BD, Lui W, Herkowitz HN, et al. Effect of anular repair on the healing strength of the intervertebral disc: A sheep model.  Spine 25:2165-2170, 2000.
     
  3. Einhorn J, Yeh O, Kamaric E, et al. Stability of a mechanical barrier used to seal anular defects.  Proceedings of the Fifth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS5). New York, NY, 2005.
     
  4. Yeh O, Chow S, Small M, et al.  Novel approach to closing anular defects: A biomechanical study. Proceedings of the Fifth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS5). New York, NY, 2005.
     
  5. Johnson WE, Wootton A, Haj AE, Einstein SM, Curtis AS, Roberts S.  Topographical guidance of intervertebral disc cell growth in vitro: towards the development of tissue repair strategies for the anulus fibrosus. Eur Spine J 15(Suppl 3):S389-S396, 2006.
     
  6. Vernon-Roberts BB, Moore RJ, Fraser RD.  The natural history of age-related disc degeneration: The pathology and sequelae of tears.  Spine 32(25):2797-2804, 2007.
     
  7. Phillips F, Pimenta L, Ferree B, Turner S, Seim H, Sickle DV.  In vivo effects of a novel anular repair device in sheep.  Proceedings of 22nd North American Spine Society (NASS). The Spine Journal 7:34S-35S, 2007.
     
  8. Ledet E, Carl A, Glennon J, Jeshurn W, DeDeyne P, Belden C.  Small intestine submucosa for anular repair: Long-term response in an in vivo sheep model.  Proceedings of 22nd North American Spine Society (NASS). The Spine Journal 7:57S, 2007.
     
  9. Phillips F, Pimenta L, Spenciner D, Paller D, Rich R, Ferree B.  Biomechanical evaluation of a novel anular repair device.  Proceedings of 22nd North American Spine Society (NASS). The Spine Journal 7:71S-72S, 2007. 
     
  10. Veres SP, Robertson PA, Broom ND.  Microstructure and mechanical disruption of the lumbar disc anulus: How the anulus fails under hydrostatic pressure.  Spine 33(25):2711-2720, 2008.
     
  11. Heuer F, Ulrich S, Claes L, Wilke HJ.  Biomechanical evaluation of conventional anulus fibrosus closure methods required for nucleus replacement.  J Neurosurg Spine 9:307-313, 2008.
     
  12. Bron JL, Helder MN, Meisel HJ, Royen BJ, Smit TH.  Repair, regenerative and supportive therapies of the anulus fibrosus: achievements and challenges.  Eur Spine J 18:301-313, 2009.
     
  13. Ledet EH, Jeshuran W, Glennon JC, Shaffrey C, DeDyne P, Belden C, Kallakury B, Carl AL.  Small intestine submucosa for anular defect closure: Long-term response in an in vivo sheep model.  Spine 34(4):1457-1463, 2009.


G.  Clinical Science of Discectomy and Anular Repair

  1. Yasargil MG. Microsurgical operation of herniated lumbar disc.  Adv Neurosurg 4:81, 1977.
     
  2. Lehmann TR, Titus MK.  Refinements in technique for open lumbar discectomy. Proceedings of the International Society for the Study of the Lumbar Spine (ISSLS). June 1997.
     
  3. Hu R, et al.  Population-based study of reoperation rates after back surgery.  Spine 22:2265-2271, 1997.
     
  4. Malter A, et al. Five-year re-operation rates after different types of lumbar surgery.  Spine 23:814-820, 1998.
     
  5. Atlas S, et al. Surgical and non-surgical management of sciatica secondary to lumbar disc herniation: Five-year outcomes from the Maine Lumbar Study. Spine 26:1179-1187, 2001.
     
  6. Asch HL, Lewis PF, Moreland DB, et al. Prospective multiple outcomes study of outpatient lumbar microdiscectomy: Should 75% to 80% success rates be the norm? J Neurosurg 96(1 Suppl):34-44, 2002.
  7. Osterman H, Sund R, Seitsalo S, et al. Risk of multiple re-operations after lumbar discectomy.  Spine 28:621-627, 2003.
     
  8. Carragee EJ, Han MY Suen PW, Kim D. Clinical outcomes after lumbar discectomy for sciatica: The effects of fragment type and anular competence. J Bone Joint Surg Am 85-A:102-108, 2003.
     
  9. Atlas S, et al. Long-term outcome of surgical and nonsurgical management of sciatica to a lumbar herniation: Ten-year results from the Maine Lumbar Spine Study. Spine 30:927-935, 2005.
     
  10. Kamaric E, Yeh O, Velagic A, et al.  Restoration of disc competency by increasing disc height using anular closure device.  Proceedings of the Fifth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS5). New York, NY, 2005.
     
  11. Yeh O, Chow S, Small M, Einhorn J, Labrecht G.  Pressure: Implications for explusion testing of intra-discal devices.  Proceedings of the Sixth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS6). Montreal, Quebec, Canada, 2006.
     
  12. Gorensek M, Vilendecic M, Eustacchio S, Trummer M, Eskinja N, Ledic D, Lambrecht G, Kamaric E, Yeh O.  Clinical investigation of the Intrinsic Therapeutics Barricaid; a novel device for closing defects in the anulus.  Proceedings of the Sixth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS6). Montreal, Quebec, Canada, 2006.
     
  13. Ledic D, Vilendecic M, Gorensek M, Varga P, Eustacchio S, Trummer M, Eskinja N, Einhorn J, Yeh O, Kamaric E, Lambrecht G.  Prospective controlled one-year clinical results on the Intrinsic Therapeutics Barricaid; a device for closing defects in the anulus.  Proceedings of 22nd North American Spine Society (NASS). The Spine Journal 7:123S-124S, 2007.
     
  14. Gorensek M, Vilendecic M, Eustacchio S, Trummer M, Eskinja N, Ledic D, Varga P, Lambrecht G, Einjorn J, Kamaric E, Yeh O.  Early clinical results with the Intrinsic Therapeutics Barricaid® Anular Repair Device - Comparison to a prospective control group. Proceedings of the Seventh Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS7). Berlin, Germany, 2007.
     
  15. Kamaric E, Gorensek M, Eustacchio S, Trummer M, Varga P, Vilendecic M, Eskinja N, Ledic D, Yeh O, EInhorn J, Lambrecht G.  Surgical factors affecting reherniation rate and disc height after lumbar discectomy: The need for anular closure and preliminary clinical results of the Barricaid® Mesh.   Proceedings of the Seventh Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS7). Berlin, Germany, 2007. 
     
  16. Carragee EJ, Spinnickie AO, Alamin TF, Paragioudakis S.  A prospective controlled study of limited versus subtotal posterior discectomy: Short-term outcomes in patients with herniated lumbar intervertebral discs and large posterior anular defect.  Spine 31:653-657, 2006.
     
  17. Vilendecic M, Ledic D, Eustacchio S, Varga P, Gorensek M.  BARRICAID ARD (Anular Reconstruction Device) in the treatment of lumbar disc herniations: A prospective study.  Proceedings of the Ninth Global Symposium on Motion Preservation Technology, Spine Arthroplasty Society (SAS9). London, England, 2009.  
     
  18. Watters WC, McGirt MJ.  An evidence-based review of the literature on the consequences of conservative versus aggressive discectomy for the treatment of primary disc herniation with radiculopathy.  The Spine J 9:240-257, 2009.
     
  19. McGirt MJ, Ambrossi GLG, Datoo G, Sciubba DM, Witham F, Wolinsky JP, Gokaslan ZL, Bydon A. Recurrent disc herniation and long-term back pain after primary lumbar discectomy: Review of outcomes reported for limited versus aggressive disc removal. Neurosurgery 64:338-345, 2009.

H.  SPORT/Disc Herniation Trial

  1. Weinstein JN, Lurie JD, Tosteson TD, et al. Surgical versus non-operative treatment of lumbar disc herniation - The Spine Patient Outcomes Research Trial (SPORT) observational cohort. JAMA 296(20):2451-2459, 2006.
     
  2. Weinstein JN, Tosteson TD, Lurie JD, et al. Surgical versus non-operative treatment of lumbar disc herniation - The Spine Patient Outcomes Research Trial (SPORT): A randomized trial. JAMA 296(20):2441-2450, 2006.
     
  3. Atlas SJ, Tosteson TD, Blood EA, Skinner JS, Pransky GS, Weinstein JN.  The impact of workers' compensation on outcomes of surgical and non-operative therapy for patients with a lumbar disc herniation: SPORT.  Spine 2010, Jan 1;35(1):89-97.
     
  4. Weinstein JN, Lurie JD, Tosteson TD, Tosteson AN, Blood EA, Abdu WA, Herkowitz H, Hilibrand A, Albert T, Fischgrund J.  Surgical versus non-operative treatment for lumbar disc herniation: four-year results for the Spine Patient Outcomes Research Trial (SPORT). Spine 2008, Dec 1;33(25):2789-800.
     
  5. Tosteson AN, Skinner JS, Tosteson TD, Lurie JD, Andersson GB, Berven S, Grove MR, Hanscom B, Blood EA, Weinstein JN.  The cost effectiveness of surgical versus non-operative treatment for lumbar disc herniation over two years: evidence from the Spine Patient Outcomes Research Trial (SPORT).  Spine 2008, Sep 1;33(19):2108-15.
  6. Pearson AM, Blood EA, Frymoyer JW, Herkowitz H, Abdu WA, Woodward R, Longley M, Emery SE, Lurie JD, Tosteson TD, Weinstein JN.  SPORT lumbar intervertebral disc herniation and back pain: does treatment, location, or morphology matter?  Spine 2008, Feb 15;33(4):428-35.
     
  7. Vaccaro AR, Fehlings MG. The applicability of clinical equipoise and sham surgery in patients with symptomatic lumbar radiculopathy due to a herniated disc: the SPORT trial.  Spine 2007, Sep 1;32(19):2039-40.
     
  8. Mazanec D, Okereke L.  Interpreting the Spine Patient Outcomes Research Trial. Medical versus surgical treatment of lumbar disc herniation: implications for future trials.  Cleve Clin J Med 2007, Aug;74(8):577-83.

I.  Economics

  1. Shvartzman L, Weingarten E, Sherry H, et al. Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc.  Spine 17:176-182, 1992.
  2. Malter AD, Larson EB, Larson EB, et al.  Cost effectiveness of lumbar discectomy for the treatment of herniated intervertebral disc.  Spine 21:1048-1055, 1996.
     
  3. Malter AD, Weinstein J. Cost effectiveness of lumbar discectomy.  Spine 21:69S-74S, 1006.
     
  4. Schoeggl A, Reddy M, Matula C.  Functional and economic outcome following microdiscectomy for lumbar disc herniation in 672 patients.  J Spinal Disord 16:150-5, 2003.
     
  5. Hansson E, Hansson T.  The cost-utility of lumbar disc herniation surgery.  Eur Spine J 16:329-337, 2007.
     
  6. Van Den Hout WB,Peul WC, Koes BW, et al for the Hague Spine Intervention Prognostic Study Group.  Prolonged conservative care versus early surgery in patients with sciatica from lumbar disc herniation: Cost-utility analysis alongside a randomized controlled trial.  BMJ 336:1351-1354, 2008.
     
  7. Tosteson ANA, Skinner JS, Tosteson TD, Lurie JD, Andersson GB, Berven S, Grove MR, Hanscom B, Blood EA, Weinstein JN.  The cost effectiveness of surgical versus non-operative treatment for lumbar disc herniation over two years: Evidence from the Spine Patient Outcomes Research Trial (SPORT).  Spine 33(19):2108-2115, 2008
     
  8. Ambrossi GL, McGirt MJ, Sciubba DM, et al.  Recurrent lumbar disc herniation after single-level lumbar discectomy: Incidence and health care cost analysis.  Neurosurgery 65(3):57.
Updated on: 09/21/11
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