Abnormal Calcium Metabolism in Adolescent Idiopathic Scoliosis

· (a- Health Service Research Grant, Hong Kong)

BMD was evaluated in 600 AIS girls & 308 normal girls aged 11-16-y by using DXA and pQCT. Pubertal growth & calcium (Ca) intake were also assessed. During pubertal period, over 20% and 2% of AIS girls were osteopenic & osteo-porotic using BMD based Z-scores. Ca intake of AIS was significantly higher than that of controls (440 ± 349 mg/d vs. 349 ± 225 mg/d, P<0.001), and was also significantly correlated with BMD (P = 0.048 to < 0.0001). Although Ca intake of AIS was relatively higher, BMD was still significantly lower than that of controls indicating an abnormal Ca homeostasis and bone metabolism in AIS patients.

· If noted, the author indicates something of value received. The codes are identified as: a-research or institutional support; b-miscellaneous funding; c-royalties; d-stock options.