FDA is recommending health care professionals discontinue prescribing and dispensing prescription combination drug products that contain more than 325 milligrams (mg) of acetaminophen per tablet, capsule, or other dosage unit.
Despite the widespread use of oral corticosteroids for acute radiculopathy resulting from a herniated lumbar disk, this treatment did not significantly improve pain levels compared with placebo in a randomized controlled trial published in the May 19 issue of JAMA. Oral steroids were linked to a modest improvement in function in this study.
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