Clinical Trial Knowledge Center

Clinical Trial for Patients with Degenerative Disc Disease

Wallis System (interspinous process implant)
The Wallis study is intended for people with mild to moderate lumbar degenerative disc disease. The Wallis device is a spinal implant that is surgically inserted between the spine's vertebrae. The device is designed to relieve low back pain caused by degeneration or damage to a spinal disc. Disc degeneration can change the normal movement and overall strength of the spine. Additionally, a degenerated disc may lose its ability to act as a shock absorber, which is important for day-to-day, pain-free living. Unlike fusion surgeries, the Wallis device is designed to stabilize the spine without joining or "fusing" vertebrae.
To learn about this clinical trial click here.

Clinical Trials for Patients Suffering Spinal Stenosis

coflex^® Spine Study: Take a Stand Against Spinal Stenosis
The coflex medical device is in the new generation of dynamic stabilization implants designed to reduce nerve compression and create spinal stability while working to return the spine to a state that more closely resembles its normal physiology. A clinical research study is currently enrolling patients to determine the safety and effectiveness of the coflex dynamic stabilization implant as compared to pedicle screw fixation and spinal fusion.
To learn about this clinical trial, call 1-866-493-9510, or click here.

Stabilimax NZ^® Dynamic Spine Stabilization System
The Stabilimax NZ^® is a medical device designed to treat lumbar spinal stenosis. It offers "dynamic stabilization" utilizing a dual-spring mechanism to help stabilize the spine at one or two levels while preserving motion in that area. Implantation of the Stabilimax NZ^® can be performed with a traditional surgical approach and a brief hospital stay.
To learn about this clinical trial, call 1-866-257-1527, or click here.

Total Facet Arthroplasty System™ (TFAS™) | FAQ
Have you been diagnosed with moderate to severe lumbar spinal stenosis? If you meet this study’s criteria, you could be a candidate to participate in the TFAS™ clinical trial. TFAS™ is a modular spinal device intended to replace diseased facet joints following surgical removal. TFAS™ offers an alternative to rigid spinal fusion. TFAS™ may eliminate the need to harvest bone graft from the hip, preserves intervertebral motion, and restores spinal stability.
To learn about this clinical trial click here.

Cleveland Clinic: Research and Clinical Trials

Already a major center for spine related treatment and research, the Cleveland Clinic Spine Institute is developing unique technologies, new specialties and collaborative approaches for effectively managing back and neck disorders. Much of the research takes place within the Spine Research Laboratory, where studies in spinal biomechanics, pathogenesis of disc degeneration, microelectromechanical systems (MEMS), and nanotechnology are being conducted.
To learn more, click here.

CAFE Study - Cancer Patient Fracture Evaluation

Cancer treatments, including chemotherapy and steroids, are associated with enhanced bone loss and increased fracture risk. This bone loss may lead to collapsed vertebrae in the spine, also known as vertebral body compression fractures (VCFs). The primary purpose of this study is to document how patients with VCFs function in every day activities after being treated with balloon kyphoplasty compared to those treated with non-surgical therapy alone. This information may help doctors treating cancer patients with broken backbones determine which treatment to recommend.
To learn about this clinical trial click here.

Spine Research Centers for Clinical Trial Information

The Spine Research Centers provide you with information about spine-related research and clinical trials in your area. The Spine Research Centers feature multiple research locations across the United States, both with nonsurgical and surgical care, and quality control from SpineMark’s Medical Advisory Board and the Institutional Review Board or IRB.
To find the nearest Research Site, call 888-652-BACK, or click here.