What You Need to Know About Non-Steroidal Anti-Inflammatory Medications: Who Should Avoid NSAIDs and Allergic Reactions

- Diabetes that is difficult to control
- Known kidney disease
- Known liver disease
- Known allergies to medications, especially aspirin
- Active peptic ulcer disease (stomach ulcers or previous history of stomach ulcer bleeding)
- Bleeding problems (people who have a history of prolonged bleeding time or who bruise easily)
- High blood pressure that is difficult to control
- Active congestive heart failure
- Asthma that worsens when taking aspirin

Can NSAIDs cause allergic reactions?
Very rarely, a nonsteroidal anti-inflammatory agent can cause a generalized allergic reaction known as anaphylactic shock. If this happens, it generally occurs soon after the person starts taking the NSAID. The symptoms of this reaction include:

- Swollen eyes, lips, or tongue
- Difficulty swallowing
- Shortness of breath
- Rapid heart rate
- Chest pain
- Decrease in sedation

If any of these symptoms occur, call 9-1-1 or have someone drive you to the nearest emergency room immediately.

Before medication is prescribed, tell your health care provider:

- If you are allergic to any medications.

- If you are currently taking any other medications (including over-the-counter medications).

- If you are pregnant or think you might be pregnant.

- If you have problems taking any medications.

Before you start taking any new medication, ask your health care provider:

- What is the name of the medication?

- Why do I need to take it?

- How often should I take it?

- What time of day should I take it?

- Should I take it on an empty stomach or with meals?

- Where should I store the medication?

- What should I do if I forget to take a dose?

- How long should I expect to take the medication?

- How will I know it is working?

- What side effects should I expect?

- Will the medication interfere with driving, working or other activities?

- Does the medication interact with any foods, alcohol or other medications (including over-the-counter medications)?

This information is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition.