What You Need to Know About Non-Steroidal Anti-Inflammatory Medications: Side Effects

Please note: The side effects listed on this page are the most common side effects. All possible side effects are not included. Always contact your health care provider if you have questions about your particular medication.

The most frequently-reported side effects of NSAIDs are gastrointestinal symptoms, such as:

- Gas
- Feeling bloated
- Heartburn
- Stomach pain
- Nausea
- Vomiting
- Diarrhea and/or constipation

These side effects can generally be relieved by taking the drug with adequate amounts of food. If the symptoms continue, the NSAID may need to be stopped. You should contact your health care provider if the symptoms listed above do not stop after a few days of taking the NSAID with food.

Some other side effects of NSAIDs include:

- Dizziness
- Feeling lightheaded
- Problems with balance
- Difficulty concentrating
- Mild headaches

If these symptoms continue for more than a few days, stop taking the NSAID and contact your health care provider for more instructions.

What side effects should I tell my health care provider about right away?
If you experience any of the following side effects, it is important to call your health care provider right away.

- Fluid retention (recognized by swelling around the ankles, feet, lower legs, hands and possibly around the eyes)
- Unusual weight gain
- Black stools

Can I take NSAIDs if I'm being treated for high blood pressure?
Nonsteroidal anti-inflammatory agents can raise blood pressure in some people. Some people with known high blood pressure (hypertension) may have to stop taking NSAIDs, if they notice their blood pressure increases in spite of taking their blood pressure medications and following their diet.

This information is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition.