Conclusions
Spine pain is one of the most common reasons for a physician visit in the United
States. Numerous spine surgeries are performed each day for treatment, and in
many cases, post-operative success has been shown to improve with the use of
pre-operative discography as an aid to surgical planning. It has been felt by
some that a positive pain response by discography is necessary for diagnosis
and surgical planning because there is an equal chance that these disc levels
may or may not be responsible for the production of a patient's symptoms. Furthermore,
MRI does not reliably predict or replace discography.
Psychological factors have been implicated in the development of new onset
spine pain following discography. This is not surprising, and is a concept that
is likely applicable to any pain generating procedure. The pain threshold differs
on an individual basis, and those with psychological factors such as depression
have been known to have a lower pain threshold.
Spine surgery is associated with a significant morbidity and mortality. It
does not seem prudent to perform a high-risk operation without a definitive
diagnosis. Due to the multitude of presentations of spinal pain, in many cases,
without discography, a definitive diagnosis is not made. This alone would be
justification for discography in the majority of situations. Discography may
prevent patients from undergoing unnecessary surgery in many cases, and this
is a very important consideration. Grubb's article found that discography was
essential to adequately identify abnormal levels in patients being considered
for spinal fusion surgery, and that roentgenograms and myelograms alone were
inadequate (35). Discography may prevent patients from undergoing surgery unnecessarily,
and this is an important consideration.
A patient with coronary artery stenosis would not be subjected to the risks
of coronary artery bypass grafting surgery unless a definitive diagnosis was
made by cardiac catheterization first, if time allowed. Cardiac catheterization
is an invasive procedure involving contrast, with significant risks of it's
own. It assists with the pre-operative planning to allow execution of a strategic
plan in the operating room. Similarly, when appropriate, discography should
be performed to assist with a proper treatment plan in the evaluation of a patient
with cervical or lumbar discogenic pain.
Cardiac catheterization is a skill that requires fellowship training of at
least two years after one has completed residency. At the present time, there
is no such requirement with regards to discography and many other interventional
procedures. People are attempting various interventional techniques after a
weekend or weeklong course at times. Perhaps there should be a fellowship-training
requirement to regulate interventional spine procedure performance, as there
is a fellowship-training requirement for cardiac catheterization?
With all of these things being said, why does the controversy over the validity
of discography continue? This question was best answered by Nikolai Bogduk,
from Australia, in 1996 when he said the following:
"The tragedy of discography is that instead of being evaluated and proven
under strict scientific guidelines such as those that apply to new drugs,
discography was popularized and adopted before it's validity and utility were
determined. On the one hand, this has resulted in improper use of discography
in some quarters. On the other hand, motivated investigators have had to catch
up, trying to justify its use retrospectively. The controversies that have
arisen pertain not so much to the biological basis of discography but stem
rather from how discography has been misunderstood and misrepresented by it's
opponents or how it has been misused by unscrupulous operators."(27)
Techniques and technology have changed significantly, decreasing the complication
rate associated with discography. Fellowships, although not required, are offered
in which the proper skills can be taught to minimize the potential complications
associated with the procedure. Discography can be performed safely and provide
valuable diagnostic information when it is undertaken in sterile conditions
by those well experienced with the procedure (19), and when those with a genuine
enthusiasm for learning these techniques and using them in the proper indications
are given the opportunity to do so.
References
1. Palit M, Schofferman J, Goldthwaite N. Anterior Discectomy and Fusion for
the Management of Neck Pain. Spine 1999; Vol.24 (21): 2224.
2. Kikuchi S, Macnab I, Moreau P. Localisation of the Level of Symptomatic
Cervical Disc Degeneration. J Bone Joint Surg (BR) 1981; 63:272-7.
3. Simmons EH, Bhalla SK. Anterior Cervical Discectomy and Fusion. A clinical
and biomechanical study with eight-year follow-up. J Bone Joint Surg (BR)
1969; 51: 225-37.
4. Colhoun E, McCall IW, Williams L, Pullicino VNC. Provocation discography
as a guide to planning operations on the spine. J Bone Joint Surg (BR)
1988; 2:267-71.
5. Murtagh FR, Arrington JA. Computer tomographically guided discography as
a determinant of normal disc level before fusion. Spine 1992; 17:826-830.
6. Guyer R, Ohnmeiss D. Lumbar discography. Position statement from the North
American Spine: Society Diagnostic and Therapeutic Committee. Spine 1995;
20:2048-59.
7. Holt EP, Jr. Fallacy of cervical discography. JAMA 1964; 188:799-801.
8. Holt EP, Jr. Further reflections on cervical discography. JAMA 1975;
231:613-4.
9. Zeidman SM, Thompson K, Ducker TB. Complications of cervical discography:
analysis of 4400 diagnostic disc injections. Neurosurgery. 1995; 37 (3):
414-7.
10. Connor PM, Darden BV. Cervical discography complications and clinical efficacy.
Spine 1993; 18 (14): 2035-8.
11. Laun A, Lorenz R, Agnoli AL. Complications of cervical discography. Journal
of Neurosurgical Sciences 1981; 25(1): 17-20.
12. Horton WC, Daftari TK. Which disk as visualized by magnetic resonance imaging
is actually a source of pain? A correlation between magnetic resonance imaging
and discography. Spine 1992; 6:S164-S171.
13. Zucherman J, Derby R, Hsu K, Picetti G, Kaiser J, Schofferman J, Goldthwaite
N, White A. Normal magnetic resonance imaging with abnormal discography. Spine
1988; 12: 1355-1359.
14. Holt EP. The question of lumbar discography. J Bone Joint Surg 1968;
59A: 720-726.
15. Carragee EJ, Chen Y, Tanner C, Hayward C, Rossi M, Hagle C. Can discography
cause long term back symptoms in previously asymptomatic subjects? Spine
2000; 25(14): 1803-1808.
16. Ohnmeiss D, Vanharanta H, Guyer R. The association between pain drawings
and computed tomographic / discographic pain responses. Spine 1995; 20
(6): 729-733.
17. Schellhas KP, Smith MD, Gundry CR, Pollie SR. Cervical discogenic pain:
prospective correlation of magnetic resonance imaging and discography in asymptomatic
subjects and pain sufferers. Spine 1996; 21: 300-12.
18. Ohnmeiss D, Guyer RD, Mason SL. The relationship between cervical discographic
pain responses and radiographic images. Clin J Pain 2000; 16(1): 1-5.
19. Guyer RD, Ohnmeiss DD, Mason SL, Shelokov AP. Complications of cervical
discography: findings in a large series. J Spinal Dosord 1997; 10: 95-101.
20. Carragee EJ, Tanner CM, Yang B, Brito JL, Truong T. False-positive findings
on lumbar discography. Reliability of subjective concordance assessment during
provocative disc injection. Spine 1999; 24 (23): 2542-2547.
21. Walsh T, Weinstein J, Spratt K et al. Lumbar discography in normal subjects:
A controlled prospective study. J Bone Joint Surg (Am) 1990; 72: 1081-8.
22. Roth DA. Cervical analgesic discography. A new test for the definitive
diagnosis of the painful-disk syndrome. JAMA 1976; 235: 1713-1715.
23. Bernard TN. Lumbar discography followed by computed tomography. Refining
the diagnosis of low-back pain. Spine 1990; 15(7): 690-706.
24. Moneta GB, Videman T, Kaivanto C, et al. Reported pain during lumbar discography
as a function of annular ruptures and disc degeneration. Spine 1994;
19: 1968-74.
25. Slipman CW, Patel RK, Zhang L, Vresilovic E, Lenrow D, Shin C, Herzog R.
Side of symptomatic annular tear and site of low back pain. Is there a correlation?
Spine 2001; 26 (8): E165-9.
26. Newman MH, Gristead GL. Anterior lumbar interbody fusion for internal disc
disruption. Spine 1992; 17: 831-3.
27. Bogduk N, Modic M. Controversy. Lumbar Discography. Spine 1996;
21 (3): 402-4.
28. Block AR, Vanharanta H, Ohnmeiss DD, Guyer RD. Discogenic pain report.
Influence of psychological factors. Spine 1996; 21 (3): 334-8.
29. Whitecloud TS, Seago RA. Cervical discogenic syndrome. Results of operative
intervention in patients with positive discography. Spine 1987; 12 (4):
313-6.
30. Motimaya A, Arici M, George D, Ramsby G. Diagnostic value of cervical discography
in the management of cervical discogenic pain. Connecticut Medicine 2000;
64 (7): 395-8.
31. Seibenrock KA, Aebi M. Cervical discography in discogenic pain syndrome
and its predictive value for cervical fusion. Archives of Orthopaedic and
Trauma Surgery 1994; 113(4): 199-203.
32. Garvey TA, Transfeldt EE, Malcolm JR, Kos P. Outcome of anterior cervical
discectomy and fusion as perceived by patients treated for dominant axial-mechanical
cervical spine pain. Spine 2002; 27 (17):1887-95.
33. Schofferman J, Garges K, Goldthwaite N, Koestler M, Libby E. Upper cervical
anterior discectomy and fusion improves discogenic cervical headaches. Spine
2002 27(20) 2240-4.
34. Grubb SA, Kelly CK. Cervical discography: clinical implications from 12
years of experience. Spine 2000-6-1 25(11) 1382-9.
35. Grubb SA, Lipscomb HJ, Guilford WB. The relative value of lumbar roentgenograms,
metrizamide myelography and discography in the assessment of patients with chronic
low-back syndrome. Spine 1987-4-1 12(3) 282-6.