The Discography Controversy: Conclusions

Conclusions and References

Faisel M. Zaman, MD, FAAPMR, ABPM
Director, Interventional Physiatry
Utah Spine and Joint Specialists, PLCC
Murray, UT
Curtis W. Slipman, MD
Director, The Penn Spine Center
University of Pennsylvania Medical Center
Philadelphia, PA
Conclusions
Spine pain is one of the most common reasons for a physician visit in the United States. Numerous spine surgeries are performed each day for treatment, and in many cases, post-operative success has been shown to improve with the use of pre-operative discography as an aid to surgical planning. It has been felt by some that a positive pain response by discography is necessary for diagnosis and surgical planning because there is an equal chance that these disc levels may or may not be responsible for the production of a patient's symptoms. Furthermore, MRI does not reliably predict or replace discography.

Psychological factors have been implicated in the development of new onset spine pain following discography. This is not surprising, and is a concept that is likely applicable to any pain generating procedure. The pain threshold differs on an individual basis, and those with psychological factors such as depression have been known to have a lower pain threshold.

Spine surgery is associated with a significant morbidity and mortality. It does not seem prudent to perform a high-risk operation without a definitive diagnosis. Due to the multitude of presentations of spinal pain, in many cases, without discography, a definitive diagnosis is not made. This alone would be justification for discography in the majority of situations. Discography may prevent patients from undergoing unnecessary surgery in many cases, and this is a very important consideration. Grubb's article found that discography was essential to adequately identify abnormal levels in patients being considered for spinal fusion surgery, and that roentgenograms and myelograms alone were inadequate (35). Discography may prevent patients from undergoing surgery unnecessarily, and this is an important consideration.

A patient with coronary artery stenosis would not be subjected to the risks of coronary artery bypass grafting surgery unless a definitive diagnosis was made by cardiac catheterization first, if time allowed. Cardiac catheterization is an invasive procedure involving contrast, with significant risks of it's own. It assists with the pre-operative planning to allow execution of a strategic plan in the operating room. Similarly, when appropriate, discography should be performed to assist with a proper treatment plan in the evaluation of a patient with cervical or lumbar discogenic pain.

Cardiac catheterization is a skill that requires fellowship training of at least two years after one has completed residency. At the present time, there is no such requirement with regards to discography and many other interventional procedures. People are attempting various interventional techniques after a weekend or weeklong course at times. Perhaps there should be a fellowship-training requirement to regulate interventional spine procedure performance, as there is a fellowship-training requirement for cardiac catheterization?

With all of these things being said, why does the controversy over the validity of discography continue? This question was best answered by Nikolai Bogduk, from Australia, in 1996 when he said the following:

"The tragedy of discography is that instead of being evaluated and proven under strict scientific guidelines such as those that apply to new drugs, discography was popularized and adopted before it's validity and utility were determined. On the one hand, this has resulted in improper use of discography in some quarters. On the other hand, motivated investigators have had to catch up, trying to justify its use retrospectively. The controversies that have arisen pertain not so much to the biological basis of discography but stem rather from how discography has been misunderstood and misrepresented by it's opponents or how it has been misused by unscrupulous operators."(27)

Techniques and technology have changed significantly, decreasing the complication rate associated with discography. Fellowships, although not required, are offered in which the proper skills can be taught to minimize the potential complications associated with the procedure. Discography can be performed safely and provide valuable diagnostic information when it is undertaken in sterile conditions by those well experienced with the procedure (19), and when those with a genuine enthusiasm for learning these techniques and using them in the proper indications are given the opportunity to do so.

References
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Last Updated: 11/30/2005

Steven Richeimer, MD

This paper presents a very nice review of the arguments supporting the use of discography. However, patients should be aware that data and opinions that contradict the use of discography have also been widely published, and the subject continues to stir considerable debate among medical specialists. Of particular note is that this article does not mention one of the most important papers that is critical of discography, the winner of the 2000 Volvo Award Winner in Clinical Studies: Lumbar High-Intensity Zone and Discography in Subjects Without Low Back Problems --Carragee EJ, Paragioudakis SJ, Khurana S:, Spine 25(23):Dec 2000.

This study found that discography into discs with "high intensity zones [HIZ]"(the usual pre-discography MRI finding) provoked significant pain in 70% of patients, whether or not the patient suffered with low back pain. Interestingly, psychological distress or chronic pain may be more important predictors of the discogram results than the presence of back pain. Discography into discs with HIZs was positive in 50% of patients with normal psychometric testing, but was 100% positive in patients with abnormal psychometric testing or chronic pain.

So, is there a role for discography? Perhaps, but the parameters for valid use have not yet been determined. While Dr. Zaman presents a positive view of discography, patients should be aware that the debate remains unsettled, and other specialists would present a more critical viewpoint. As with all medical care, patients are encouraged to carefully discuss their treatment with their physician and seek a second opinion if needed.