Complications of Posterior Fusion and Instrumentation for Degenerative Lumbar Scoliosis

Kyu-Jung Cho, M.D., Ph.D.
Inha University Hospital
Incheon, Korea
Se Il Suk, M.D.
Emeritus Professor
Inje University Sanggye Paik Hospital
Seoul, Korea
Seung Rim Park, MD
Jin-Hyok Kim, M.D.
Seoul Spine Institute, Inje University, Sanggye Paik Hospital
Seoul, Korea
Abstract from the 2006 SRS Annual Meeting
Purpose: To investigate the incidence and risk factors of complications in posterior fusion and instrumentation for degenerative lumbar scoliosis

Methods: 47 patients (average age 66.6, range 48 to 83) of degenerative lumbar scoliosis undergoing posterior instrumentation with a minimum 2-yr follow-up were analyzed. The average levels of fusion was 4.7±2.2 segments. The upper instrumented vertebra was T10 in 10 patients, L1 in 6 patients, and L2 in 15 patients. The lower instrumented vertebra was L5 in 22 patients, and sacrum in 24 patients. 7 patients had additional PLIF at the lower lumbar spine. We evaluated the early perioperative (<3 mo after surgery) and late complications.

Results: The complications were more likely in older patients (>65 years) than younger patients (P=0.05). 28 patients had major co-morbidities including hypertension, diabetes and heart disease. The two or more co-morbidities had the tendency to increase early complications with no statistical significance (P>0.05). Mean EBL was 2106±1083ml. More than 2000ml of blood loss increased early complications with a statistical difference (P=0.01). Operative time and fusion lengths were not associated with complications. There were 14 early perioperative complications and 18 late complications. There was 1 mortality case by pulmonary embolism. Early complications included G-I problems in 5 patients, postoperative delirium in 2 patients, superficial infection in 2 patients, and transient neurologic deficit in 1 patient. Late complications included 2 pseudarthrosis and 16 adjacent segment diseases. Adjacent segment disease developed at proximal segment in 11 patients and at distal segment in 5 patients. Revision surgery was performed in 6 patients for pseudarthrosis and adjacent segment disease. (See Table)

Conclusion: The overall incidence of complications of posterior fusion and instrumentation for degenerative lumbar scoliosis was 68%. Older age and abundant blood loss were risk factors for early perioperative complications. However, there was no factor related with late complications.

Table. Risk factors of complications

 
Early complications (n)
Late complications (n)
Age (years): less than or equal to 65 (n=17)
2

7

Age (years): greater than or equal to 65 (n=30)
12
(P=0.5)

11
(P=0.77)

Gender: M(n=8)
1

2

Gender: F (n=39)
13
(P=0.4)

16
(P=6.9)

Smoking: Yes (n=6)
1

3

Smoking: No (n-41)
13
(P=0.65)

13
(P=0.66)

No. of co-morbidity: 0 (n=20)
8

8

No. of co-morbidity: 1 (n=19)
2

6

No. of co-morbidity: less than or equal to 2 (n=8)
4
(P›0.05)

4
(P=0.65)

Blood loss (ml): less than or equal to 2000 (n=24)
3

9

Blood loss (ml): › 2000 (n-23)
11
(P=0.01)

9
(P=0.91)

Op. time (min): less than or equal to 200 (n=25)
5

8

Op. time (min): › 200 (n=22)
9
(P=0.2)

10
(P=0.38)

Fusion level: less than or equal to 4 (n=28)
6

11

Fusion level: › 4 (n=19)
8
(P=0.19)

7
(P=0.87)

Cobb angle (°): less than or equal to 20 (n=27)
7

8

Cobb angle (°): › 20 (n=20)
7
(P=0.54)

10
(P=0.23)

Lumbar lordosis (°): less than or equal to 30 (n=23)
7

8

Lumbar lordosis (°): › 30 (n=24)
7
(P=0.9)

10
(P=0.77)

Last Updated: 03/12/2007