Infections Following Spinal Deformity Surgery: a Twenty-Year Assessment of 2876 Patients

Jacob Buchowski, MD, MS
Washington University School of Medicine
St. Louis, MO
Lawrence G. Lenke, MD
The Jerome J. Gilden Professor of Orthopedic Surgery
Co-Chief Pediatric & Adult Spinal, Scoliosis & Reconstructive Surgery
St. Louis, MO
Craig A. Kuhns, MD
Washington University School of Medicine
St. Louis, MO
Ronald A. Lehman, Jr.
Washington University Medical School
St. Louis, MO
Abstract from the 2006 SRS Annual Meeting
Purpose: To evaluate post-operative infections in adult and pediatric patients undergoing spinal deformity surgery at one institution over a twenty-year period (1985-2005) in order to determine risk factors, examine treatment strategies, and analyze clinical outcome.

Materials and Methods: The medical records of 2876 adult and pediatric patients who underwent spinal deformity surgery (greater than or equal to 5 levels) at one institution were analyzed. Patients who developed a wound infection requiring formal debridement in the operating room were identified.

Results: Of the 2876 patients who were treated surgically for spinal deformity, 69 patients (41 females and 28 males) with an average age of 25.1±18.6 years developed a postoperative wound infection requiring a debridement in the operating room, for an overall infection rate of 2.4%. Sixty-five patients (94.2%) had a posterior wound infection and the remaining four patients (5.8%) had an anterior wound infection. The overall infection rate was 2.1% (39/1897) in pediatric patients (<18 years of age) and 3.1% (30/979) in adult patients (greater than or equal to 18 age). The risk developing a postoperative wound infection was large part determined by the patient's underlying diagnosis as is illustrated table below. average time from surgery until noted 470±859 days (range, 4 11.3 years). Patients were treated with irrigation debridement appropriate antibiotics. Implants not removed unless absolutely necessary. With treatment 39.1% (27/69) achieved solid fusion only 26.1% (18/69) required removal implants.

Conclusion: Post-operative wound infection can be a devastating complication; fortunately, however, the risk of developing a post-operative wound infection following spinal deformity surgery is reasonably low (2.4%) and varies considerably depending on the patient's underlying diagnosis. With appropriate treatment a large percentage of patients can expect to achieve solid fusion and only a minority will require removal of implants.

Diagnosis
Patients w/Infection
Total Patients
Infection Rate (%)
Neuromuscular Scoliosis
18
495
3.6
Congenital Kyphosis/Scoliosis/Kyphoscoliosis
11
372
4.0
Adolescent Idiopathic Scoliosis
9
1031
0.9
Adult Idiopathic Scoliosis
6
369
1.6
Degenerative Scoliosis
5
81
6.2
Fixed Sagittal Imbalance
5
71
7.0
Trauma
3
64
4.7
Charcot Spine
3
9
33.3
Kyphosis
1
126
0.8
Infantile Scoliosis
1
23
4.3
Scheuermann's Disease
1
54
1.9
Other
6
281
2.5
Total
69
2876
2.4
Last Updated: 03/12/2007