Thoracolumbar Deformity Arthrodesis Stopping at L5: Fate of the L5-S1 Disc with a Minimum 5-Year Follow-Up

Craig A. Kuhns, MD
Washington University School of Medicine
St. Louis, MO
Keith Bridwell, MD
Orthopaedic Surgeon
Washington University School of Medicine
St. Louis, MO
Lawrence G. Lenke, MD
The Jerome J. Gilden Professor of Orthopedic Surgery
Co-Chief Pediatric & Adult Spinal, Scoliosis & Reconstructive Surgery
St. Louis, MO
Courtney Amor
Abstract from the 2006 SRS Annual Meeting
Background: Two previous studies reported the results of long deformity fusions terminating at L5 with minimum 2-year follow-up only.

Purpose: Evaluate the fate of L5-S1 disc analyzing subsequent disc degeneration and associated risk factors for degeneration.

Methods: Thirty consecutive patients with an average age 45years(20-62yo)were fused from the thoracic spine to L5 and were evaluated at a mean follow-up of 8.7 years(5-15.5). Patients were evaluated preoperatively, postoperatively, and latest follow-up with radiograps and SRS scores. Disc degeneration utilizing validated radiographic Weiner grades. Grade 0-1 discs were "healthy" and grade 2-3 were degenerated. Patients with "healthy" discs preop that subsequently degenerated were designated subsequent advanced degeneration(SAD).

Results: 2/30 patients had preoperative advanced degeneration of the L5-S1 disc(Weiner Grade 2-3). 28/30 patients were assessed as "healthy discs" preop (Weiner Grade 0-1). By latest follow-up, subsequent advanced L5-S1 disc degeneration(SAD) developed in 19 of these 28 patients(68%) who had "healthy" discs. Younger age at the time of surgery is an associated risk factor for developing SAD(p=0.04). Preop sagittal balance was not significantly different between those patients that developed SAD and those who did not. 17/30 patients(57%) were noted to have sagittal imbalance >5cm at follow-up. At most recent follow-up the average sagittal imbalance in the SAD group was 72mm. In the "healthy" group it was 3mm (p=0.001). 6/30 patients(20%) were revised with extension to the sacrum. There was a trend toward inferior SRS pain scores at follow-up in SAD patients(avg. score-4.0 vs 3.2,p=0.08).

Conclusion: Advanced L5-S1 DDD developed in 68% of deformity patients after long fusions to L5 with 5-15 year follow-up. SAD frequently results in significant positive sagittal balance with minimum 5year follow-up.

Last Updated: 03/12/2007