Clinical Trial Knowledge Center

Clinical trials are key in the advancement of spine care. Patients who qualify may benefit by receiving expert care at leading medical facilities. These same patients are paving the way for new technologies to help future patients, as well.
 

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Featured Clinical Trials

Freedom® Lumbar Disc in the Treatment of Lumbar Degenerative Disc Disease

This study will look at the result of using the Freedom® Lumbar Disc (FLD) device as an artificial lumbar disc. Clinical trial participants with degenerative disc disease will be randomized to disc arthroplasty with the FLD device or a control device. The overall objective of this trial is to collect clinical data to demonstrate the safety and effectiveness of FLD used for the treatment of symptomatic lumbar degenerative disc disease compared to the control device.

DIAM™ Spinal Stabilization System Clinical Trial

For Patients with Degenerative Disc Disease
The purpose of this randomized study is to establish the safety and effectiveness of the DIAM™ Spinal Stabilization System in the treatment of moderate single-level lumbar degenerative disc disease. Patients enrolled in the study will be randomly assigned to receive either the investigational DIAM™ Device or non-surgical treatment that involves medication, physical therapy, patient education and spinal injections. Patients enrolled in the study must be evaluated by their surgeon at regular intervals.

Gene Mapping of Inherited Spinal Disorders (Scoliosis and Degenerative Disc Disease)

The identification of genetic markers linked to Scoliosis and Degenerative Disc Disease. By understanding the molecular causes for these conditions, Axial Biotech hopes to be able to develop diagnostic/prognostic tests and potentially improved treatment options. Individuals who will be considered for eligibility include: Men, women, and children who have a diagnosis of Scoliosis or Degenerative Disc Disease.

IDE Clinical Trial Comparing coflex® vs. Fusion to Treat Lumbar Spinal Stenosis (coflex)

The coflex medical device is in the new generation of dynamic stabilization implants designed to reduce nerve compression and create spinal stability while working to return the spine to a state that more closely resembles its normal physiology. A clinical research study is currently enrolling patients to determine the safety and effectiveness of the coflex dynamic stabilization implant as compared to pedicle screw fixation and spinal fusion.

Facet Replacement System to Treat Spinal Stenosis

The purpose of this study is to determine if the ACADIA™ Facet Replacement System is effective in the treatment of lumbar spinal stenosis. The primary objective of the study is to evaluate the overall success rate of the ACADIA™ Facet Replacement System in patients with lumbar spinal stenosis when compared to a posterior spinal fusion control.

Superion™ Interspinous Spacer in Lumbar Spinal Stenosis

Investigational device designed to treat moderate lumbar spinal stenosis
The Superion™ Interspinous Spacer is an investigational medical device designed to relieve chronic pain caused by moderate lumbar spinal stenosis and may offer a minimally invasive alternative to traditional spinal surgery. This may avoid the need for a large incision, and minimizing bleeding and trauma to the body.

Crosstrees Medical Clinical Trial to Evaluate the Performance of Crosstrees™ System in Reducing Pain and Decreasing the Risk of Cement Leakage in Vertebral Compression Fractures

The Crosstrees™ System uses a fabric Pod to control the delivery of bone cement to fractured vertebral bodies. This study is being performed to evaluate the Crosstrees System performance in reducing pain and decreasing the risk of cement leakage associated with vertebroplasty and kyphoplasty.

DISCOVER™ Artificial Cervical Disc Compared with Anterior Cervical Discectomy and Fusion for Treatment of Cervical Degenerative Disc Disease

Investigational Device Exemption (IDE) Study
If you are between 21 and 70 years of age, have been diagnosed with cervical Degenerative Disc Disease (DDD), have recurring neck and/or arm pain for at least 6 weeks despite taking prescription medicine or other therapy, and are able to receive surgery and participate in all follow-up procedures, you may be a candidate for this clinical trial.