Paul Santiago, MD's portrait
Paul Santiago, MD
Assistant Professor of Neurological Surgery
Washington University School of Medicine
Saint Louis, MO

About Paul Santiago, MD

Paul Santiago, MD, joins the Department of Neurological Surgery as assistant professor, specializing in minimally invasive spinal surgery, complex disorders of the spine and spinal cord, spinal instrumentation and traumatic disorders of the nervous system in addition to general neurosurgery.

Dr. Santiago is a Stanford University graduate and earned his medical degree from Yale University in New Haven, CT. He completed a general surgery internship and neurosurgical residency at the University of Washington, Seattle. He also completed a spine fellowship at the University of Chicago Hospitals.

His areas of clinical interest include complex disorders of the spine and spinal cord. He has extensive training in minimally invasive spinal surgery, including endoscopic spinal surgery, spinal instrumentation, and the management of cranial and spinal injury. Dr. Santiago is pursuing scientific investigation into the molecular basis of tumor metastasis to bone and the treatment of cancer-related pain in the spine.

Publications

1. Santiago P, Fessler RG: Minimally invasive surgery for the management of cervical spondylosis. Neurosurgery. Accepted for publication May, 2004.

 

2. Isaacs RE, Sandhu FA, Santiago P, Vodichetty VK, Aronson O, Kelly K. Hrubes M, Fessler, RG: Thoracic Microendoscopic Discectomy. Spine. Accepted for publication May, 2004.

3. Sandhu FA, Santiago P, Palmer S, Fessler RG: Minimally Invasive Surgical Treatment of Synovial Cysts. Neurosurgery, 54:107-11, 2004.

4. Mesiwala AH, Farrell L, Santiago P, Ghatan S, Silbergeld DL: The effects of hydrogen peroxide on brain and brain tumors. Surg Neurol, 59: 398-407, 2003.

5. Mourad P, Farrell L, Stamps L, Santiago P, Fillmore H, Broaddus W, Silbergeld D: Quantitative assessment of glioblastoma invasion in vivo. Cancer Letters, 192: 97-107, 2003.

6. Schuster JM, Santiago P, Elliott JP, Grady MS, Newell DW, Winn HR. Acute traumatic posteroinferior cerebellar artery aneurysms: report of three cases. Neurosurgery, 45: 1465-7; discussion 1467-8, 1999.

7. Fukuhara T, McKhann GM, 2nd, Santiago P, Eskridge JM, Loeser JD, Winn HR. Resolution of central pain after embolization of an arteriovenous malformation. Case report. J Neurosurg, 90: 575-9, 1999.

8. Inoue D, Santiago P, Horne WC, Baron R. Identification of an osteoclast transcription factor that binds to the human T-cell leukemia virus type I-long terminal repeat enhancer element. J. Biol. Chem., 272: 25386-93, 1997.

9. Lipka JJ, Santiago P, Chan L, Reyes GR, Samuel KP, Blattner WA, Shaw GM, Hanson CV, Sninsky JJ, Foung SKH. Modified Western blot assay for confirmation and differentiation of human T-cell lymphotropic virus types I and II. J. Inf. Dis., 164: 40-3, 1991.

Abstracts and Presentations

1. Trent L. Tredway,MD, Paul Santiago, MD, Bong-Soo Kim,MD, Laurie Rice, RN NP, and Richard G. Fessler, MD, PhD. Removal of far lateral herniated discs via a minimally-invasive technique Abstract. Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

2. Trent L. Tredway,MD, Paul Santiago, MD, Bong-Soo Kim,MD, Max Lee,MD, and Richard G. Fessler, MD, PhD. Resection of spinal intradural neoplasms via a minimally-invasive technique Abstract. Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

3. Trent L. Tredway,MD, Paul Santiago, M.D., Bong-Soo Kim, M.D., Laurie Rice, RN, NP and Richard G. Fessler, M.D., Ph.D. Two level minimally-invasive transforaminal lumbar interbody fusion (MI-TLIF) with three arm SextantTMinstrumentation Abstract. Annual Meeting Joint Section AANS/CNS on Spinal Disorders and Peripheral Nerve, San Diego, 2004.

4. Sandhu FA, Santiago P, Palmer S, Fessler RG: Minimally invasive surgical treatment of lumbar synovial cysts. Abstract. Annual Meeting of the Congress of Neurological Surgery. Denver, 2003.

5. Santiago P, Sandhu FA, Fessler RG: Microendoscopic technique for the management of cervical spinal canal stenosis. Abstract. Annual Meeting of the Congress of Neurological Surgery. Denver, 2003.

6. Perez-Cruet MJ, Sandhu FA, Santiago P, Issacs RE, Fessler RG: Minimally invasive microendoscopic thoracic discectomy. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

7. Isaacs R, Aaronssen O, Santiago P, Sandhu F, Fessler, RG: Percutaneous thoracic pedicel screw placement. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

8. Issacs RE, Aaronssen O, Sandhu FA, Santiago P, Fessler, RG: Thoracic microendoscopic discectomy. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

9. Perez-Cruet MJ, Santiago P, Sandhu FA, Foley KT, Fessler RG: Accuracy and safety of percutaneous pedicle screw placemenr for degenerative lumbar disease. Abstract. Annual Meeting of the American Association of Neurological Surgeons, San Diego, 2003.

10. Mesiwala A, Santiago P, Ghatan S, Farrell L, Silbergeld D: Affects of hydrogen peroxide on human and rat brain and brain tumors. Abstract, Society for Neuro-Oncology, 2000.

11. Santiago P, Farrell L, Silbergeld D: In Vitro evaluation of ethanol and peroxide for resection cavity application following pituitary microadenoma resection. Abstract, Annual Meeting of the American Association of Neurological Surgeons, San Francisco, 2000.

12. Mourad P, Mesiwala A, Farrell L, Sokolov D, Vaezy S, Santiago P, Mayberg MR, Crum L, Silbergeld DL: Ultrasound opens the blood brain barrier without damage in vivo. Abstract, IEEE International Ultrasonics Symposium, 1999.

13. Santiago P, Farrell L, Silbergeld D: Chemosensitivity profiles of glioblastoma cell lines derived from gross tumor and from invading cells. Abstract, Annual Meeting of the American Association of Neurological Surgeons, New Orleans, 1999

14. Santiago P, Spence AM, Silbergeld D. Stelzer KJ: Re-resection and low activity I-125 brachytherapy for recurrent glioblastoma. Abstract, American Association of Neurological Surgeons, New Orleans, 1999

15. Santiago P, Ojemann G, Silbergeld D. Surgical disruption of the arcuate fasciculus does not result in aphasias. Abstract, Annual Meeting American Epilepsy Society, San Diego, 1998.

16. Santiago P, Kulkarni A, Yaswen L, Karlsson S. Development of a TGF-ß1 double knockout embryonic stem cell line for use as an in vitro model of early development and differentiation. Presented at the 10th Annual International Medical Student Congress, Istanbul, Turkey, 1994.

17.Santiago P, Horne WC, Neff L, Horowitz M, Li CB, Ruddle NH, Baron R. Osteoclast restricted and 1,25 (OH)2 Vitamin D3 dependent expression of the tax gene product in HTLV-I tax transgenic mice. Abstract, 14th Annual Meeting of the American Society for Bone and Mineral Research, Minneapolis, 1992.

18. Hadlock KG, Lipka JJ, Santiago P, Bui KL, Moeckli R, et al. Cloning and analysis of an HTLV-II specific recombinant antigen from the envelope region of HTLV-II. Abstract, 4th International Conference on Human Retrovirology: HTLV, Montego Bay, Jamaica, 1991.

19. Lipka JJ, Santiago P, Chan L, Reyes GR, Hanson CV, Blattner WA, Foung SKH. One step serological confirmation and typing of HTLV-I/II infection. Abstract. Annual Meeting of the American Association of Neurological Surgeons, New Orleans, 1999.

Book Chapters

1. Santiago P, Fine AD, Shafron D, Fessler RG: Benign Extradural Lesions of the Dorsal Spine in Youman's Neurological Surgery, Fourth Edition, WB Saunders Co., Philadelphia, 2003.

2. Santiago P, Fessler RG: Trauma Surgery Fractures of the Lumbar and Sacral Spine in Spine Surgery: Techniques, Complication Avoidance and Management, Churchill Livingstone, Philadelphia, 2003. In preparation.

3. Santiago P, Fessler RG: Lumbar microendoscopic Laminoforaminotomy and Discectomy in Endoscopic Spinal Surgery, Thieme, New York, 2003. Submitted for publication..

4. Santiago P, Fessler RG: Trauma of the Nervous System in Neurology in Clinical Practice, Fourth Edition, Elsevier Publishing, Co., St, Louis, 2003. In preparation.

5. Santiago P, Silbergeld D: Malignant Gliomas in Youman's Neurological Surgery, Fourth Edition, WB Saunders Co., Philadelphia, 2003. In Press.

6. Santiago, P, Silbergeld D: Pharmacology and Utility of Common Neurosurgical Drugs, in Textbook of Neurological Surgery, 2nd Edition, Lipincott Williams and Wilkins, 2002.

Submitted for Publication

1. Isaacs RE, Santiago P, Sandhu FA, Podichetty VK, Kelly K, Rice L, Fessler RG: Minimally Invasive Microendoscopic Assisted Transforaminal Lumbar Interbody Fusion with Instrumentation. The Spine Journal. June 2003.

Articles Written by Paul Santiago, MD

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